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The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. Debeuf N, et al. Among authors: lemeire k. J Allergy Clin Immunol. 2019 Dec;144(6):1648-1659.e9. doi: 10.1016/j.jaci.2019.06.041. Epub 2019 Jul 20. J Allergy Clin Immunol. 2019. PMID: 31330218 Free PMC article.
Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer.
Loret N, Vandamme N, De Coninck J, Taminau J, De Clercq K, Blancke G, Jonckheere S, Goossens S, Lemeire K, De Prijck S, Verstaen K, Seurinck R, Van Dorpe J, Weyers S, Denys H, Van de Vijver K, Lambrecht BN, Tummers P, Saeys Y, Berx G. Loret N, et al. Among authors: lemeire k. Mol Cancer Res. 2022 Oct 4;20(10):1532-1547. doi: 10.1158/1541-7786.MCR-21-0565. Mol Cancer Res. 2022. PMID: 35749080
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Devos M, Gilbert B, Denecker G, Leurs K, Mc Guire C, Lemeire K, Hochepied T, Vuylsteke M, Lambert J, Van Den Broecke C, Libbrecht L, Haigh J, Berx G, Lippens S, Vandenabeele P, Declercq W. Devos M, et al. Among authors: lemeire k. J Invest Dermatol. 2017 Feb;137(2):494-505. doi: 10.1016/j.jid.2016.09.026. Epub 2016 Oct 7. J Invest Dermatol. 2017. PMID: 27725202 Free article.
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.
Denecker G, Vandamme N, Akay O, Koludrovic D, Taminau J, Lemeire K, Gheldof A, De Craene B, Van Gele M, Brochez L, Udupi GM, Rafferty M, Balint B, Gallagher WM, Ghanem G, Huylebroeck D, Haigh J, van den Oord J, Larue L, Davidson I, Marine JC, Berx G. Denecker G, et al. Among authors: lemeire k. Cell Death Differ. 2014 Aug;21(8):1250-61. doi: 10.1038/cdd.2014.44. Epub 2014 Apr 25. Cell Death Differ. 2014. PMID: 24769727 Free PMC article.
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification.
Pieters T, Goossens S, Haenebalcke L, Andries V, Stryjewska A, De Rycke R, Lemeire K, Hochepied T, Huylebroeck D, Berx G, Stemmler MP, Wirth D, Haigh JJ, van Hengel J, van Roy F. Pieters T, et al. Among authors: lemeire k. PLoS Genet. 2016 Aug 24;12(8):e1006243. doi: 10.1371/journal.pgen.1006243. eCollection 2016 Aug. PLoS Genet. 2016. PMID: 27556156 Free PMC article.
A new mouse model to study the role of ectopic Nanos3 expression in cancer.
Andries V, De Keuckelaere E, Staes K, Hochepied T, Taminau J, Lemeire K, Birembaut P, Berx G, van Roy F. Andries V, et al. Among authors: lemeire k. BMC Cancer. 2019 Jun 17;19(1):598. doi: 10.1186/s12885-019-5807-x. BMC Cancer. 2019. PMID: 31208373 Free PMC article.
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies.
Pieters T, T'Sas S, Demoen L, Almeida A, Haenebalcke L, Matthijssens F, Lemeire K, D'Hont J, Van Rockeghem F, Hochepied T, Lintermans B, Reunes L, Lammens T, Berx G, Haigh JJ, Goossens S, Van Vlierberghe P. Pieters T, et al. Among authors: lemeire k. Sci Rep. 2019 Jul 22;9(1):10577. doi: 10.1038/s41598-019-46853-x. Sci Rep. 2019. PMID: 31332244 Free PMC article.
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