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Vaginal concentrations of lactic acid potently inactivate HIV.
Aldunate M, Tyssen D, Johnson A, Zakir T, Sonza S, Moench T, Cone R, Tachedjian G. Aldunate M, et al. Among authors: tachedjian g. J Antimicrob Chemother. 2013 Sep;68(9):2015-25. doi: 10.1093/jac/dkt156. Epub 2013 May 8. J Antimicrob Chemother. 2013. PMID: 23657804 Free PMC article.
Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition.
Hearps AC, Tyssen D, Srbinovski D, Bayigga L, Diaz DJD, Aldunate M, Cone RA, Gugasyan R, Anderson DJ, Tachedjian G. Hearps AC, et al. Among authors: tachedjian g. Mucosal Immunol. 2017 Nov;10(6):1480-1490. doi: 10.1038/mi.2017.27. Epub 2017 Apr 12. Mucosal Immunol. 2017. PMID: 28401934 Free article.
Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.
Tyssen D, Wang YY, Hayward JA, Agius PA, DeLong K, Aldunate M, Ravel J, Moench TR, Cone RA, Tachedjian G. Tyssen D, et al. Among authors: tachedjian g. mSphere. 2018 Jul 5;3(4):e00055-18. doi: 10.1128/mSphere.00055-18. mSphere. 2018. PMID: 29976641 Free PMC article.
Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota.
Delgado-Diaz DJ, Tyssen D, Hayward JA, Gugasyan R, Hearps AC, Tachedjian G. Delgado-Diaz DJ, et al. Among authors: tachedjian g. Front Cell Infect Microbiol. 2020 Jan 10;9:446. doi: 10.3389/fcimb.2019.00446. eCollection 2019. Front Cell Infect Microbiol. 2020. PMID: 31998660 Free PMC article.
The Effect of Exogenous Sex Steroids on the Vaginal Microbiota: A Systematic Review.
Ratten LK, Plummer EL, Bradshaw CS, Fairley CK, Murray GL, Garland SM, Bateson D, Tachedjian G, Masson L, Vodstrcil LA. Ratten LK, et al. Among authors: tachedjian g. Front Cell Infect Microbiol. 2021 Nov 12;11:732423. doi: 10.3389/fcimb.2021.732423. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34869054 Free PMC article.
103 results