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Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model.
Anthony-Gonda K, Bardhi A, Ray A, Flerin N, Li M, Chen W, Ochsenbauer C, Kappes JC, Krueger W, Worden A, Schneider D, Zhu Z, Orentas R, Dimitrov DS, Goldstein H, Dropulić B. Anthony-Gonda K, et al. Among authors: worden a. Sci Transl Med. 2019 Aug 7;11(504):eaav5685. doi: 10.1126/scitranslmed.aav5685. Sci Transl Med. 2019. PMID: 31391322 Free PMC article.
Bispecific anti-CD20, anti-CD19 CAR T cells for relapsed B cell malignancies: a phase 1 dose escalation and expansion trial.
Shah NN, Johnson BD, Schneider D, Zhu F, Szabo A, Keever-Taylor CA, Krueger W, Worden AA, Kadan MJ, Yim S, Cunningham A, Hamadani M, Fenske TS, Dropulić B, Orentas R, Hari P. Shah NN, et al. Among authors: worden aa. Nat Med. 2020 Oct;26(10):1569-1575. doi: 10.1038/s41591-020-1081-3. Epub 2020 Oct 5. Nat Med. 2020. PMID: 33020647 Clinical Trial.
Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma.
Jackson Z, Roe A, Sharma AA, Lopes FBTP, Talla A, Kleinsorge-Block S, Zamborsky K, Schiavone J, Manjappa S, Schauner R, Lee G, Liu R, Caimi PF, Xiong Y, Krueger W, Worden A, Kadan M, Schneider D, Orentas R, Dropulic B, Sekaly RP, de Lima M, Wald DN, Reese JS. Jackson Z, et al. Among authors: worden a. Front Immunol. 2020 Aug 7;11:1941. doi: 10.3389/fimmu.2020.01941. eCollection 2020. Front Immunol. 2020. PMID: 32849651 Free PMC article.
Multiple site place-of-care manufactured anti-CD19 CAR-T cells induce high remission rates in B-cell malignancy patients.
Maschan M, Caimi PF, Reese-Koc J, Sanchez GP, Sharma AA, Molostova O, Shelikhova L, Pershin D, Stepanov A, Muzalevskii Y, Suzart VG, Otegbeye F, Wald D, Xiong Y, Wu D, Knight A, Oparaocha I, Ferencz B, Roy A, Worden A, Kruger W, Kadan M, Schneider D, Orentas R, Sekaly RP, de Lima M, Dropulić B. Maschan M, et al. Among authors: worden a. Nat Commun. 2021 Dec 10;12(1):7200. doi: 10.1038/s41467-021-27312-6. Nat Commun. 2021. PMID: 34893603 Free PMC article.
Recurring seasonality exposes dominant species and niche partitioning strategies of open ocean picoeukaryotic algae.
Eckmann CA, Bachy C, Wittmers F, Strauss J, Blanco-Bercial L, Vergin KL, Parsons RJ, Kudela RM, Johnson R, Bolaños LM, Giovannoni SJ, Carlson CA, Worden AZ. Eckmann CA, et al. Among authors: worden az. Commun Earth Environ. 2024;5(1):266. doi: 10.1038/s43247-024-01395-7. Epub 2024 May 20. Commun Earth Environ. 2024. PMID: 38779128 Free PMC article.
3D intrusions transport active surface microbial assemblages to the dark ocean.
Freilich MA, Poirier C, Dever M, Alou-Font E, Allen J, Cabornero A, Sudek L, Choi CJ, Ruiz S, Pascual A, Farrar JT, Johnston TMS, D'Asaro EA, Worden AZ, Mahadevan A. Freilich MA, et al. Among authors: worden az. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2319937121. doi: 10.1073/pnas.2319937121. Epub 2024 May 2. Proc Natl Acad Sci U S A. 2024. PMID: 38696469
189 results