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Opposing T cell responses in experimental autoimmune encephalomyelitis.
Saligrama N, Zhao F, Sikora MJ, Serratelli WS, Fernandes RA, Louis DM, Yao W, Ji X, Idoyaga J, Mahajan VB, Steinmetz LM, Chien YH, Hauser SL, Oksenberg JR, Garcia KC, Davis MM. Saligrama N, et al. Among authors: steinmetz lm. Nature. 2019 Aug;572(7770):481-487. doi: 10.1038/s41586-019-1467-x. Epub 2019 Aug 7. Nature. 2019. PMID: 31391585 Free PMC article.
Assembly of functionally integrated human forebrain spheroids.
Birey F, Andersen J, Makinson CD, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR, Paşca SP. Birey F, et al. Among authors: steinmetz lm. Nature. 2017 May 4;545(7652):54-59. doi: 10.1038/nature22330. Epub 2017 Apr 26. Nature. 2017. PMID: 28445465 Free PMC article.
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Miller CN, et al. Among authors: steinmetz lm. Nature. 2018 Jul;559(7715):627-631. doi: 10.1038/s41586-018-0345-2. Epub 2018 Jul 18. Nature. 2018. PMID: 30022164 Free PMC article.
Targeted Perturb-seq enables genome-scale genetic screens in single cells.
Schraivogel D, Gschwind AR, Milbank JH, Leonce DR, Jakob P, Mathur L, Korbel JO, Merten CA, Velten L, Steinmetz LM. Schraivogel D, et al. Among authors: steinmetz lm. Nat Methods. 2020 Jun;17(6):629-635. doi: 10.1038/s41592-020-0837-5. Epub 2020 Jun 1. Nat Methods. 2020. PMID: 32483332 Free PMC article.
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19.
Li J, Zaslavsky M, Su Y, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Aditya Mallajosyula VV, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2021 Dec 25:2021.12.23.473930. doi: 10.1101/2021.12.23.473930. bioRxiv. 2021. PMID: 34981055 Free PMC article. Updated. Preprint.
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Among authors: steinmetz lm. Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591. Epub 2022 Apr 15. Science. 2022. PMID: 35258337 Free PMC article.
217 results