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Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years.
Cantó E, Barro C, Zhao C, Caillier SJ, Michalak Z, Bove R, Tomic D, Santaniello A, Häring DA, Hollenbach J, Henry RG, Cree BAC, Kappos L, Leppert D, Hauser SL, Benkert P, Oksenberg JR, Kuhle J. Cantó E, et al. Among authors: tomic d. JAMA Neurol. 2019 Nov 1;76(11):1359-1366. doi: 10.1001/jamaneurol.2019.2137. JAMA Neurol. 2019. PMID: 31403661 Free PMC article.
Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis.
Chitnis T, Gonzalez C, Healy BC, Saxena S, Rosso M, Barro C, Michalak Z, Paul A, Kivisakk P, Diaz-Cruz C, Sattarnezhad N, Pierre IV, Glanz BI, Tomic D, Kropshofer H, Häring D, Leppert D, Kappos L, Bakshi R, Weiner HL, Kuhle J. Chitnis T, et al. Among authors: tomic d. Ann Clin Transl Neurol. 2018 Oct 16;5(12):1478-1491. doi: 10.1002/acn3.638. eCollection 2018 Dec. Ann Clin Transl Neurol. 2018. PMID: 30564615 Free PMC article.
Blood neurofilament light as a potential endpoint in Phase 2 studies in MS.
Sormani MP, Haering DA, Kropshofer H, Leppert D, Kundu U, Barro C, Kappos L, Tomic D, Kuhle J. Sormani MP, et al. Among authors: tomic d. Ann Clin Transl Neurol. 2019 May 28;6(6):1081-1089. doi: 10.1002/acn3.795. eCollection 2019 Jun. Ann Clin Transl Neurol. 2019. PMID: 31211172 Free PMC article.
Serum neurofilament light chain levels associations with gray matter pathology: a 5-year longitudinal study.
Jakimovski D, Kuhle J, Ramanathan M, Barro C, Tomic D, Hagemeier J, Kropshofer H, Bergsland N, Leppert D, Dwyer MG, Michalak Z, Benedict RHB, Weinstock-Guttman B, Zivadinov R. Jakimovski D, et al. Among authors: tomic d. Ann Clin Transl Neurol. 2019 Sep;6(9):1757-1770. doi: 10.1002/acn3.50872. Epub 2019 Aug 22. Ann Clin Transl Neurol. 2019. PMID: 31437387 Free PMC article.
Serum neurofilament light chain is a useful biomarker in pediatric multiple sclerosis.
Reinert MC, Benkert P, Wuerfel J, Michalak Z, Ruberte E, Barro C, Huppke P, Stark W, Kropshofer H, Tomic D, Leppert D, Kuhle J, Brück W, Gärtner J. Reinert MC, et al. Among authors: tomic d. Neurol Neuroimmunol Neuroinflamm. 2020 May 13;7(4):e749. doi: 10.1212/NXI.0000000000000749. Print 2020 Jul. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32404429 Free PMC article.
Long-term prognostic value of longitudinal measurements of blood neurofilament levels.
Häring DA, Kropshofer H, Kappos L, Cohen JA, Shah A, Meinert R, Leppert D, Tomic D, Kuhle J. Häring DA, et al. Among authors: tomic d. Neurol Neuroimmunol Neuroinflamm. 2020 Aug 12;7(5):e856. doi: 10.1212/NXI.0000000000000856. Print 2020 Sep. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32817406 Free PMC article. Clinical Trial.
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