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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Wu T, Dejanovic B, Gandham VD, Gogineni A, Edmonds R, Schauer S, Srinivasan K, Huntley MA, Wang Y, Wang TM, Hedehus M, Barck KH, Stark M, Ngu H, Foreman O, Meilandt WJ, Elstrott J, Chang MC, Hansen DV, Carano RAD, Sheng M, Hanson JE. Wu T, et al. Among authors: barck kh. Cell Rep. 2019 Aug 20;28(8):2111-2123.e6. doi: 10.1016/j.celrep.2019.07.060. Cell Rep. 2019. PMID: 31433986 Free article.
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis.
Katschke KJ Jr, Helmy KY, Steffek M, Xi H, Yin J, Lee WP, Gribling P, Barck KH, Carano RA, Taylor RE, Rangell L, Diehl L, Hass PE, Wiesmann C, van Lookeren Campagne M. Katschke KJ Jr, et al. Among authors: barck kh. J Exp Med. 2007 Jun 11;204(6):1319-25. doi: 10.1084/jem.20070432. Epub 2007 Jun 4. J Exp Med. 2007. PMID: 17548523 Free PMC article.
Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Singh M, Couto SS, Forrest WF, Lima A, Cheng JH, Molina R, Long JE, Hamilton P, McNutt A, Kasman I, Nannini MA, Reslan HB, Cao TC, Ho CC, Barck KH, Carano RA, Foreman O, Eastham-Anderson J, Jubb AM, Ferrara N, Johnson L. Singh M, et al. Among authors: barck kh. J Pathol. 2012 Aug;227(4):417-30. doi: 10.1002/path.4053. Epub 2012 Jun 28. J Pathol. 2012. PMID: 22611036
Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
Sampath D, Oeh J, Wyatt SK, Cao TC, Koeppen H, Eastham-Anderson J, Robillard L, Ho CC, Ross J, Zhuang G, Reslan HB, Vitorino P, Barck KH, Ungersma SE, Vernes JM, Caunt M, Van Bruggen N, Ye W, Vijapurkar U, Meng YJ, Ferrara N, Friedman LS, Carano RA. Sampath D, et al. Among authors: barck kh. Neoplasia. 2013 Jul;15(7):694-711. doi: 10.1593/neo.13470. Neoplasia. 2013. PMID: 23814482 Free PMC article.
29 results