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355 results

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Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity.
Ha SP, Klemen ND, Kinnebrew GH, Brandmaier AG, Marsh J, Hangoc G, Palmer DC, Restifo NP, Cornetta K, Broxmeyer HE, Touloukian CE. Ha SP, et al. Among authors: restifo np. J Clin Invest. 2010 Dec;120(12):4273-88. doi: 10.1172/JCI43274. Epub 2010 Nov 15. J Clin Invest. 2010. PMID: 21084750 Free PMC article.
Reprogramming antitumor immunity.
Crompton JG, Clever D, Vizcardo R, Rao M, Restifo NP. Crompton JG, et al. Among authors: restifo np. Trends Immunol. 2014 Apr;35(4):178-85. doi: 10.1016/j.it.2014.02.003. Epub 2014 Mar 21. Trends Immunol. 2014. PMID: 24661777 Free PMC article. Review.
Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Goff SL, Dudley ME, Citrin DE, Somerville RP, Wunderlich JR, Danforth DN, Zlott DA, Yang JC, Sherry RM, Kammula US, Klebanoff CA, Hughes MS, Restifo NP, Langhan MM, Shelton TE, Lu L, Kwong ML, Ilyas S, Klemen ND, Payabyab EC, Morton KE, Toomey MA, Steinberg SM, White DE, Rosenberg SA. Goff SL, et al. Among authors: restifo np. J Clin Oncol. 2016 Jul 10;34(20):2389-97. doi: 10.1200/JCO.2016.66.7220. Epub 2016 May 23. J Clin Oncol. 2016. PMID: 27217459 Free PMC article. Clinical Trial.
Identification of essential genes for cancer immunotherapy.
Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, Eil R, Sukumar M, Guijarro EP, Day CP, Robbins P, Feldman S, Merlino G, Zhang F, Restifo NP. Patel SJ, et al. Among authors: restifo np. Nature. 2017 Aug 31;548(7669):537-542. doi: 10.1038/nature23477. Epub 2017 Aug 7. Nature. 2017. PMID: 28783722 Free PMC article.
Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.
Vizcardo R, Klemen ND, Islam SMR, Gurusamy D, Tamaoki N, Yamada D, Koseki H, Kidder BL, Yu Z, Jia L, Henning AN, Good ML, Bosch-Marce M, Maeda T, Liu C, Abdullaev Z, Pack S, Palmer DC, Stroncek DF, Ito F, Flomerfelt FA, Kruhlak MJ, Restifo NP. Vizcardo R, et al. Among authors: restifo np. Cell Rep. 2018 Mar 20;22(12):3175-3190. doi: 10.1016/j.celrep.2018.02.087. Cell Rep. 2018. PMID: 29562175 Free PMC article.
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.
Malekzadeh P, Pasetto A, Robbins PF, Parkhurst MR, Paria BC, Jia L, Gartner JJ, Hill V, Yu Z, Restifo NP, Sachs A, Tran E, Lo W, Somerville RP, Rosenberg SA, Deniger DC. Malekzadeh P, et al. Among authors: restifo np. J Clin Invest. 2019 Mar 1;129(3):1109-1114. doi: 10.1172/JCI123791. Epub 2019 Feb 4. J Clin Invest. 2019. PMID: 30714987 Free PMC article. Clinical Trial. No abstract available.
Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Malekzadeh P, Yossef R, Cafri G, Paria BC, Lowery FJ, Jafferji M, Good ML, Sachs A, Copeland AR, Kim SP, Kivitz S, Parkhurst MR, Robbins PF, Ray S, Xi L, Raffeld M, Yu Z, Restifo NP, Somerville RPT, Rosenberg SA, Deniger DC. Malekzadeh P, et al. Among authors: restifo np. Clin Cancer Res. 2020 Mar 15;26(6):1267-1276. doi: 10.1158/1078-0432.CCR-19-1874. Epub 2020 Jan 29. Clin Cancer Res. 2020. PMID: 31996390 Free PMC article.
355 results