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Non-alcoholic fatty liver disease (NAFLD) models in drug discovery.
Cole BK, Feaver RE, Wamhoff BR, Dash A. Cole BK, et al. Among authors: wamhoff br. Expert Opin Drug Discov. 2018 Feb;13(2):193-205. doi: 10.1080/17460441.2018.1410135. Epub 2017 Dec 6. Expert Opin Drug Discov. 2018. PMID: 29190166 Review.
Drug-induced steatohepatitis.
Dash A, Figler RA, Sanyal AJ, Wamhoff BR. Dash A, et al. Among authors: wamhoff br. Expert Opin Drug Metab Toxicol. 2017 Feb;13(2):193-204. doi: 10.1080/17425255.2017.1246534. Epub 2016 Oct 27. Expert Opin Drug Metab Toxicol. 2017. PMID: 27759439 Free PMC article. Review.
Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis.
Shepherd EL, Saborano R, Northall E, Matsuda K, Ogino H, Yashiro H, Pickens J, Feaver RE, Cole BK, Hoang SA, Lawson MJ, Olson M, Figler RA, Reardon JE, Nishigaki N, Wamhoff BR, Günther UL, Hirschfield G, Erion DM, Lalor PF. Shepherd EL, et al. Among authors: wamhoff br. JHEP Rep. 2020 Nov 20;3(2):100217. doi: 10.1016/j.jhepr.2020.100217. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33490936 Free PMC article.
An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation.
Cole BK, Simmers MB, Feaver R, Qualls CW Jr, Collado MS, Berzin E, Figler RA, Pryor AW Jr, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. Cole BK, et al. Among authors: wamhoff br. Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2185-95. doi: 10.1161/ATVBAHA.115.306245. Epub 2015 Aug 20. Arterioscler Thromb Vasc Biol. 2015. PMID: 26293464
Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes.
Collado MS, Cole BK, Figler RA, Lawson M, Manka D, Simmers MB, Hoang S, Serrano F, Blackman BR, Sinha S, Wamhoff BR. Collado MS, et al. Among authors: wamhoff br. Stem Cells Transl Med. 2017 Aug;6(8):1673-1683. doi: 10.1002/sctm.17-0004. Epub 2017 Jun 19. Stem Cells Transl Med. 2017. PMID: 28628273 Free PMC article.
77 results