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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Győrffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. Diaz Osterman CJ, et al. Among authors: molinolo a. Elife. 2019 Sep 3;8:e47327. doi: 10.7554/eLife.47327. Elife. 2019. PMID: 31478830 Free PMC article.
Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing.
Sakai A, Ando M, Fukusumi T, Ren S, Liu C, Qualliotine J, Haft S, Sadat S, Saito Y, Guo TW, Xu G, Sasik R, Fisch KM, Gutkind JS, Fertig EJ, Molinolo AA, Califano JA. Sakai A, et al. Among authors: molinolo aa. PLoS One. 2020 May 21;15(5):e0233380. doi: 10.1371/journal.pone.0233380. eCollection 2020. PLoS One. 2020. PMID: 32437477 Free PMC article.
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers.
Ren S, Gaykalova DA, Guo T, Favorov AV, Fertig EJ, Tamayo P, Callejas-Valera JL, Allevato M, Gilardi M, Santos J, Fukusumi T, Sakai A, Ando M, Sadat S, Liu C, Xu G, Fisch KM, Wang Z, Molinolo AA, Gutkind JS, Ideker T, Koch WM, Califano JA. Ren S, et al. Among authors: molinolo aa. Oncogene. 2020 Oct;39(40):6327-6339. doi: 10.1038/s41388-020-01431-8. Epub 2020 Aug 26. Oncogene. 2020. PMID: 32848210 Free PMC article.
Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.
Ozmadenci D, Shankara Narayanan JS, Andrew J, Ojalill M, Barrie AM, Jiang S, Iyer S, Chen XL, Rose M, Estrada V, Molinolo A, Bertotto T, Mikulski Z, McHale MC, White RR, Connolly DC, Pachter JA, Kuchroo VK, Stupack DG, Schlaepfer DD. Ozmadenci D, et al. Among authors: molinolo a. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2117065119. doi: 10.1073/pnas.2117065119. Epub 2022 Apr 25. Proc Natl Acad Sci U S A. 2022. PMID: 35467979 Free PMC article.
Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas.
Gilardi M, Wang Z, Proietto M, Chillà A, Calleja-Valera JL, Goto Y, Vanoni M, Janes MR, Mikulski Z, Gualberto A, Molinolo AA, Ferrara N, Gutkind JS, Burrows F. Gilardi M, et al. Among authors: molinolo aa. Mol Cancer Ther. 2020 Sep;19(9):1784-1796. doi: 10.1158/1535-7163.MCT-19-0958. Epub 2020 Jul 29. Mol Cancer Ther. 2020. PMID: 32727882 Free PMC article.
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS. Wang Z, et al. Among authors: molinolo aa. Nat Commun. 2019 Dec 5;10(1):5546. doi: 10.1038/s41467-019-13471-0. Nat Commun. 2019. PMID: 31804466 Free PMC article.
Global gene expression profile of nasopharyngeal carcinoma by laser capture microdissection and complementary DNA microarrays.
Sriuranpong V, Mutirangura A, Gillespie JW, Patel V, Amornphimoltham P, Molinolo AA, Kerekhanjanarong V, Supanakorn S, Supiyaphun P, Rangdaeng S, Voravud N, Gutkind JS. Sriuranpong V, et al. Among authors: molinolo aa. Clin Cancer Res. 2004 Aug 1;10(15):4944-58. doi: 10.1158/1078-0432.CCR-03-0757. Clin Cancer Res. 2004. PMID: 15297395
212 results