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Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease.
J Med Chem. 2020 Mar 12;63(5):2074-2094. doi: 10.1021/acs.jmedchem.9b00584. Epub 2019 Sep 27.
J Med Chem. 2020.
PMID: 31525963
Studies on phenothiazines: New microtubule-interacting compounds with phenothiazine A-ring as potent antineoplastic agents.
Ghinet A, Moise IM, Rigo B, Homerin G, Farce A, Dubois J, Bîcu E.
Ghinet A, et al. Among authors: homerin g.
Bioorg Med Chem. 2016 May 15;24(10):2307-17. doi: 10.1016/j.bmc.2016.04.001. Epub 2016 Apr 1.
Bioorg Med Chem. 2016.
PMID: 27073050
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On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives.
Homerin G, Lipka E, Rigo B, Farce A, Dubois J, Ghinet A.
Homerin G, et al.
Org Biomol Chem. 2017 Oct 4;15(38):8110-8118. doi: 10.1039/c7ob01489a.
Org Biomol Chem. 2017.
PMID: 28905970
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Ultrasounds-mediated 10-seconds synthesis of chalcones as potential farnesyltransferase inhibitors.
Homerin G, Nica AS, Farce A, Dubois J, Ghinet A.
Homerin G, et al.
Bioorg Med Chem Lett. 2020 Jun 1;30(11):127149. doi: 10.1016/j.bmcl.2020.127149. Epub 2020 Mar 29.
Bioorg Med Chem Lett. 2020.
PMID: 32247731
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A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy.
Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V.
Douguet L, et al. Among authors: homerin g.
Nat Commun. 2021 Jan 28;12(1):653. doi: 10.1038/s41467-021-20912-2.
Nat Commun. 2021.
PMID: 33510147
Free PMC article.
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