Renault N - Search Results

1

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease.

Homerin G, Jawhara S, Dezitter X, Baudelet D, Dufrénoy P, Rigo B, Millet R, Furman C, Ragé G, Lipka E, Farce A, Renault N, Sendid B, Charlet R, Leroy J, Phanithavong M, Richeval C, Wiart JF, Allorge D, Adriouch S, Vouret-Craviari V, Ghinet A. Homerin G, et al. Among authors: renault n. J Med Chem. 2020 Mar 12;63(5):2074-2094. doi: 10.1021/acs.jmedchem.9b00584. Epub 2019 Sep 27. J Med Chem. 2020. PMID: 31525963

2

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

Tourteau A, Andrzejak V, Body-Malapel M, Lemaire L, Lemoine A, Mansouri R, Djouina M, Renault N, El Bakali J, Desreumaux P, Muccioli GG, Lambert DM, Chavatte P, Rigo B, Leleu-Chavain N, Millet R. Tourteau A, et al. Among authors: renault n. Bioorg Med Chem. 2013 Sep 1;21(17):5383-94. doi: 10.1016/j.bmc.2013.06.010. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23849204

3

Structural insight into PPARgamma ligands binding.

Farce A, Renault N, Chavatte P. Farce A, et al. Among authors: renault n. Curr Med Chem. 2009;16(14):1768-89. doi: 10.2174/092986709788186165. Curr Med Chem. 2009. PMID: 19442144 Review.

4

Novel structural insights for drug design of selective 5-HT(2C) inverse agonists from a ligand-biased receptor model.

Renault N, Gohier A, Chavatte P, Farce A. Renault N, et al. Eur J Med Chem. 2010 Nov;45(11):5086-99. doi: 10.1016/j.ejmech.2010.08.018. Epub 2010 Aug 12. Eur J Med Chem. 2010. PMID: 20880612

5

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis.

Andrzejak V, Muccioli GG, Body-Malapel M, El Bakali J, Djouina M, Renault N, Chavatte P, Desreumaux P, Lambert DM, Millet R. Andrzejak V, et al. Among authors: renault n. Bioorg Med Chem. 2011 Jun 15;19(12):3777-86. doi: 10.1016/j.bmc.2011.04.057. Epub 2011 May 6. Bioorg Med Chem. 2011. PMID: 21612933

6

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

Pirat C, Farce A, Lebègue N, Renault N, Furman C, Millet R, Yous S, Speca S, Berthelot P, Desreumaux P, Chavatte P. Pirat C, et al. Among authors: renault n. J Med Chem. 2012 May 10;55(9):4027-61. doi: 10.1021/jm101360s. Epub 2012 Feb 27. J Med Chem. 2012. PMID: 22260081 Review. No abstract available.

7

Switching invariant natural killer T (iNKT) cell response from anticancerous to anti-inflammatory effect: molecular bases.

Laurent X, Bertin B, Renault N, Farce A, Speca S, Milhomme O, Millet R, Desreumaux P, Hénon E, Chavatte P. Laurent X, et al. Among authors: renault n. J Med Chem. 2014 Jul 10;57(13):5489-508. doi: 10.1021/jm4010863. Epub 2014 Feb 12. J Med Chem. 2014. PMID: 24428717 Review.

8

Design, synthesis and biological evaluation of potent FAAH inhibitors.

Tuo W, Leleu-Chavain N, Barczyk A, Renault N, Lemaire L, Chavatte P, Millet R. Tuo W, et al. Among authors: renault n. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2701-5. doi: 10.1016/j.bmcl.2016.04.004. Epub 2016 Apr 23. Bioorg Med Chem Lett. 2016. PMID: 27117424

9

Antagonists of the adenosine A_2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity.

Duroux R, Agouridas L, Renault N, El Bakali J, Furman C, Melnyk P, Yous S. Duroux R, et al. Among authors: renault n. Eur J Med Chem. 2018 Jan 20;144:151-163. doi: 10.1016/j.ejmech.2017.12.007. Epub 2017 Dec 5. Eur J Med Chem. 2018. PMID: 29268131 Free article.

10

Benzo[d]thiazol-2(3H)-ones as new potent selective CB₂ agonists with anti-inflammatory properties.

Leleu-Chavain N, Baudelet D, Heloire VM, Rocha DE, Renault N, Barczyk A, Djouina M, Body-Malapel M, Carato P, Millet R. Leleu-Chavain N, et al. Among authors: renault n. Eur J Med Chem. 2019 Mar 1;165:347-362. doi: 10.1016/j.ejmech.2018.12.008. Epub 2018 Dec 13. Eur J Med Chem. 2019. PMID: 30583970

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