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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Zhu Y, Tchkonia T, Kirkland JL. Hickson LJ, et al. Among authors: khosla s. EBioMedicine. 2019 Sep;47:446-456. doi: 10.1016/j.ebiom.2019.08.069. Epub 2019 Sep 18. EBioMedicine. 2019. PMID: 31542391 Free PMC article.
Fat tissue, aging, and cellular senescence.
Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD, Kirkland JL. Tchkonia T, et al. Among authors: khosla s. Aging Cell. 2010 Oct;9(5):667-84. doi: 10.1111/j.1474-9726.2010.00608.x. Epub 2010 Aug 15. Aging Cell. 2010. PMID: 20701600 Free PMC article. Review.
Nonoxidative free fatty acid disposal is greater in young women than men.
Koutsari C, Basu R, Rizza RA, Nair KS, Khosla S, Jensen MD. Koutsari C, et al. Among authors: khosla s. J Clin Endocrinol Metab. 2011 Feb;96(2):541-7. doi: 10.1210/jc.2010-1651. Epub 2010 Dec 1. J Clin Endocrinol Metab. 2011. PMID: 21123445 Free PMC article.
Age-dependent renal cortical microvascular loss in female mice.
Urbieta-Caceres VH, Syed FA, Lin J, Zhu XY, Jordan KL, Bell CC, Bentley MD, Lerman A, Khosla S, Lerman LO. Urbieta-Caceres VH, et al. Among authors: khosla s. Am J Physiol Endocrinol Metab. 2012 Apr 15;302(8):E979-86. doi: 10.1152/ajpendo.00411.2011. Epub 2012 Feb 7. Am J Physiol Endocrinol Metab. 2012. PMID: 22318944 Free PMC article.
938 results