Buevich AV - Search Results

1

Bioactivation of GPR40 Agonist MK-8666: Formation of Protein Adducts in Vitro from Reactive Acyl Glucuronide and Acyl CoA Thioester.

Shang J, Tschirret-Guth R, Cancilla M, Samuel K, Chen Q, Chobanian HR, Thomas A, Tong W, Josien H, Buevich AV, Mitra K. Shang J, et al. Among authors: buevich av. Chem Res Toxicol. 2020 Jan 21;33(1):191-201. doi: 10.1021/acs.chemrestox.9b00226. Epub 2019 Oct 14. Chem Res Toxicol. 2020. PMID: 31566356

2

Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling.

Buevich AV, He CQ, Pio B, Samuel K, Mitra K, Sherer EC, Cancilla MT, Chobanian HR. Buevich AV, et al. Chem Res Toxicol. 2022 Mar 21;35(3):459-474. doi: 10.1021/acs.chemrestox.1c00366. Epub 2022 Feb 14. Chem Res Toxicol. 2022. PMID: 35156375

3

Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety.

Mandal M, Mitra K, Grotz D, Lin X, Palamanda J, Kumari P, Buevich A, Caldwell JP, Chen X, Cox K, Favreau L, Hyde L, Kennedy ME, Kuvelkar R, Liu X, Mazzola RD, Parker E, Rindgen D, Sherer E, Wang H, Zhu Z, Stamford AW, Cumming JN. Mandal M, et al. J Med Chem. 2018 Dec 13;61(23):10700-10708. doi: 10.1021/acs.jmedchem.8b01326. Epub 2018 Nov 15. J Med Chem. 2018. PMID: 30388368

4

Substituted 4-morpholine N-arylsulfonamides as γ-secretase inhibitors.

Zhao Z, Pissarnitski DA, Josien HB, Bara TA, Clader JW, Li H, McBriar MD, Rajagopalan M, Xu R, Terracina G, Hyde L, Song L, Zhang L, Parker EM, Osterman R, Buevich AV. Zhao Z, et al. Among authors: buevich av. Eur J Med Chem. 2016 Nov 29;124:36-48. doi: 10.1016/j.ejmech.2016.08.024. Epub 2016 Aug 13. Eur J Med Chem. 2016. PMID: 27560281

5

Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery.

Mandal M, Madeira M, Amin RP, Buevich AV, Cheng A, Labroli M, Liu X, Acton J, Pio B, Basso A, Chobanian H, Dong G, Dropinski J, Guo Y, Guo Z, Kurowski S, Korfmacher W, Lee S, Meng D, Ondeyka D, Yang Z, Zhang R, Wei H, Wu Z, Zhang F, Wollenberg G, Biftu T, Greenlee WJ, Chintala M, Maletic M, Zhu Z. Mandal M, et al. Among authors: buevich av. J Med Chem. 2022 Apr 14;65(7):5575-5592. doi: 10.1021/acs.jmedchem.1c02048. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349275

6

Homodecoupled 1,1- and 1,n-ADEQUATE: Pivotal NMR Experiments for the Structure Revision of Cryptospirolepine.

Saurí J, Bermel W, Buevich AV, Sherer EC, Joyce LA, Sharaf MH, Schiff PL Jr, Parella T, Williamson RT, Martin GE. Saurí J, et al. Among authors: buevich av. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10160-4. doi: 10.1002/anie.201502540. Epub 2015 Jul 15. Angew Chem Int Ed Engl. 2015. PMID: 26178441

7

Molecular packing of pharmaceuticals analyzed with paramagnetic relaxation enhancement and ultrafast magic angle pinning NMR.

Lu X , Tsutsumi Y , Huang C , Xu W , Byrn SR , Templeton AC , Buevich AV , Amoureux JP , Su Y . Lu X , et al. Among authors: buevich av. Phys Chem Chem Phys. 2020 Jun 21;22(23):13160-13170. doi: 10.1039/d0cp02049d. Epub 2020 Jun 4. Phys Chem Chem Phys. 2020. PMID: 32495810

8

NMR Structure Elucidation of Small Organic Molecules and Natural Products: Choosing ADEQUATE vs HMBC.

Buevich AV, Williamson RT, Martin GE. Buevich AV, et al. J Nat Prod. 2014 Aug 22;77(8):1942-7. doi: 10.1021/np500445s. J Nat Prod. 2014. PMID: 25098228

9

Synergistic Combination of CASE Algorithms and DFT Chemical Shift Predictions: A Powerful Approach for Structure Elucidation, Verification, and Revision.

Buevich AV, Elyashberg ME. Buevich AV, et al. J Nat Prod. 2016 Dec 23;79(12):3105-3116. doi: 10.1021/acs.jnatprod.6b00799. Epub 2016 Nov 22. J Nat Prod. 2016. PMID: 28006916

10

A compatibility study of a secondary amine active pharmaceutical ingredient with starch: identification of a novel degradant formed between desloratadine and a starch impurity using LC-MS(n) and NMR spectroscopy.

Yu X, Buevich AV, Li M, Wang X, Rustum AM. Yu X, et al. Among authors: buevich av. J Pharm Sci. 2013 Feb;102(2):717-31. doi: 10.1002/jps.23416. Epub 2012 Dec 14. J Pharm Sci. 2013. PMID: 23242759

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

72 results

Search Page