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Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria.
Pearce RJ, Pota H, Evehe MS, Bâ el-H, Mombo-Ngoma G, Malisa AL, Ord R, Inojosa W, Matondo A, Diallo DA, Mbacham W, van den Broek IV, Swarthout TD, Getachew A, Dejene S, Grobusch MP, Njie F, Dunyo S, Kweku M, Owusu-Agyei S, Chandramohan D, Bonnet M, Guthmann JP, Clarke S, Barnes KI, Streat E, Katokele ST, Uusiku P, Agboghoroma CO, Elegba OY, Cissé B, A-Elbasit IE, Giha HA, Kachur SP, Lynch C, Rwakimari JB, Chanda P, Hawela M, Sharp B, Naidoo I, Roper C. Pearce RJ, et al. PLoS Med. 2009 Apr 14;6(4):e1000055. doi: 10.1371/journal.pmed.1000055. Epub 2009 Apr 14. PLoS Med. 2009. PMID: 19365539 Free PMC article.
Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.
Mombo-Ngoma G, Supan C, Dal-Bianco MP, Missinou MA, Matsiegui PB, Ospina Salazar CL, Issifou S, Ter-Minassian D, Ramharter M, Kombila M, Kremsner PG, Lell B. Mombo-Ngoma G, et al. Malar J. 2011 Mar 1;10:53. doi: 10.1186/1475-2875-10-53. Malar J. 2011. PMID: 21362162 Free PMC article. Clinical Trial.
High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children.
Mombo-Ngoma G, Oyakhirome S, Ord R, Gabor JJ, Greutélaers KC, Profanter K, Greutélaers B, Kurth F, Lell B, Kun JF, Issifou S, Roper C, Kremsner PG, Grobusch MP. Mombo-Ngoma G, et al. Malar J. 2011 May 14;10:123. doi: 10.1186/1475-2875-10-123. Malar J. 2011. PMID: 21569596 Free PMC article. Clinical Trial.
Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections.
Supan C, Mombo-Ngoma G, Dal-Bianco MP, Ospina Salazar CL, Issifou S, Mazuir F, Filali-Ansary A, Biot C, Ter-Minassian D, Ramharter M, Kremsner PG, Lell B. Supan C, et al. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73. doi: 10.1128/AAC.05359-11. Epub 2012 Mar 19. Antimicrob Agents Chemother. 2012. PMID: 22430976 Free PMC article.
100 results