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Identification of a tumor-specific allo-HLA-restricted γδTCR.
Kierkels GJJ, Scheper W, Meringa AD, Johanna I, Beringer DX, Janssen A, Schiffler M, Aarts-Riemens T, Kramer L, Straetemans T, Heijhuurs S, Leusen JHW, San José E, Fuchs K, Griffioen M, Falkenburg JH, Bongiovanni L, de Bruin A, Vargas-Diaz D, Altelaar M, Heck AJR, Shultz LD, Ishikawa F, Nishimura MI, Sebestyén Z, Kuball J. Kierkels GJJ, et al. Among authors: leusen jhw. Blood Adv. 2019 Oct 8;3(19):2870-2882. doi: 10.1182/bloodadvances.2019032409. Blood Adv. 2019. PMID: 31585951 Free PMC article.
Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering.
van der Schoot JMS, Fennemann FL, Valente M, Dolen Y, Hagemans IM, Becker AMD, Le Gall CM, van Dalen D, Cevirgel A, van Bruggen JAC, Engelfriet M, Caval T, Bentlage AEH, Fransen MF, Nederend M, Leusen JHW, Heck AJR, Vidarsson G, Figdor CG, Verdoes M, Scheeren FA. van der Schoot JMS, et al. Among authors: leusen jhw. Sci Adv. 2019 Aug 28;5(8):eaaw1822. doi: 10.1126/sciadv.aaw1822. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31489367 Free PMC article.
γ9δ2T cell diversity and the receptor interface with tumor cells.
Vyborova A, Beringer DX, Fasci D, Karaiskaki F, van Diest E, Kramer L, de Haas A, Sanders J, Janssen A, Straetemans T, Olive D, Leusen J, Boutin L, Nedellec S, Schwartz SL, Wester MJ, Lidke KA, Scotet E, Lidke DS, Heck AJ, Sebestyen Z, Kuball J. Vyborova A, et al. J Clin Invest. 2020 Sep 1;130(9):4637-4651. doi: 10.1172/JCI132489. J Clin Invest. 2020. PMID: 32484803 Free PMC article.
The selection of variable regions affects effector mechanisms of IgA antibodies against CD20.
Evers M, Rösner T, Dünkel A, Jansen JHM, Baumann N, Ten Broeke T, Nederend M, Eichholz K, Klausz K, Reiding K, Schewe DM, Kellner C, Peipp M, Leusen JHW, Valerius T. Evers M, et al. Among authors: leusen jhw. Blood Adv. 2021 Oct 12;5(19):3807-3820. doi: 10.1182/bloodadvances.2021004598. Blood Adv. 2021. PMID: 34525171 Free PMC article.
143 results