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Identification of a tumor-specific allo-HLA-restricted γδTCR.
Blood Adv. 2019 Oct 8;3(19):2870-2882. doi: 10.1182/bloodadvances.2019032409.
Blood Adv. 2019.
PMID: 31585951
Free PMC article.
Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds.
van Diest E, Hernández López P, Meringa AD, Vyborova A, Karaiskaki F, Heijhuurs S, Gumathi Bormin J, van Dooremalen S, Nicolasen MJT, Gatti LCDE, Johanna I, Straetemans T, Sebestyén Z, Beringer DX, Kuball J.
van Diest E, et al. Among authors: meringa ad.
J Immunother Cancer. 2021 Nov;9(11):e003850. doi: 10.1136/jitc-2021-003850.
J Immunother Cancer. 2021.
PMID: 34815357
Free PMC article.
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Uncovering the mode of action of engineered T cells in patient cancer organoids.
Dekkers JF, Alieva M, Cleven A, Keramati F, Wezenaar AKL, van Vliet EJ, Puschhof J, Brazda P, Johanna I, Meringa AD, Rebel HG, Buchholz MB, Barrera Román M, Zeeman AL, de Blank S, Fasci D, Geurts MH, Cornel AM, Driehuis E, Millen R, Straetemans T, Nicolasen MJT, Aarts-Riemens T, Ariese HCR, Johnson HR, van Ineveld RL, Karaiskaki F, Kopper O, Bar-Ephraim YE, Kretzschmar K, Eggermont AMM, Nierkens S, Wehrens EJ, Stunnenberg HG, Clevers H, Kuball J, Sebestyen Z, Rios AC.
Dekkers JF, et al. Among authors: meringa ad.
Nat Biotechnol. 2023 Jan;41(1):60-69. doi: 10.1038/s41587-022-01397-w. Epub 2022 Jul 25.
Nat Biotechnol. 2023.
PMID: 35879361
Free PMC article.
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Strategies to improve γδTCRs engineered T-cell therapies for the treatment of solid malignancies.
Meringa AD, Hernández-López P, Cleven A, de Witte M, Straetemans T, Kuball J, Beringer DX, Sebestyen Z.
Meringa AD, et al.
Front Immunol. 2023 Jun 27;14:1159337. doi: 10.3389/fimmu.2023.1159337. eCollection 2023.
Front Immunol. 2023.
PMID: 37441064
Free PMC article.
No abstract available.
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Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells.
Hernández-López P, van Diest E, Brazda P, Heijhuurs S, Meringa A, Hoorens van Heyningen L, Riillo C, Schwenzel C, Zintchenko M, Johanna I, Nicolasen MJT, Cleven A, Kluiver TA, Millen R, Zheng J, Karaiskaki F, Straetemans T, Clevers H, de Bree R, Stunnenberg HG, Peng WC, Roodhart J, Minguet S, Sebestyén Z, Beringer DX, Kuball J.
Hernández-López P, et al.
Nat Immunol. 2024 Jan;25(1):88-101. doi: 10.1038/s41590-023-01665-0. Epub 2023 Nov 27.
Nat Immunol. 2024.
PMID: 38012415
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CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A.
Mamedov MR, et al. Among authors: meringa ad.
Nature. 2023 Sep;621(7977):188-195. doi: 10.1038/s41586-023-06482-x. Epub 2023 Aug 30.
Nature. 2023.
PMID: 37648854
Free PMC article.
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