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Regulation of lifespan by neural excitation and REST.
Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaiácovo MP, Yankner BA. Zullo JM, et al. Among authors: o hern p. Nature. 2019 Oct;574(7778):359-364. doi: 10.1038/s41586-019-1647-8. Epub 2019 Oct 16. Nature. 2019. PMID: 31619788 Free PMC article.
Decreased function of survival motor neuron protein impairs endocytic pathways.
Dimitriadi M, Derdowski A, Kalloo G, Maginnis MS, O'Hern P, Bliska B, Sorkaç A, Nguyen KC, Cook SJ, Poulogiannis G, Atwood WJ, Hall DH, Hart AC. Dimitriadi M, et al. Among authors: o hern p. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4377-86. doi: 10.1073/pnas.1600015113. Epub 2016 Jul 11. Proc Natl Acad Sci U S A. 2016. PMID: 27402754 Free PMC article.
Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
Baskoylu SN, Yersak J, O'Hern P, Grosser S, Simon J, Kim S, Schuch K, Dimitriadi M, Yanagi KS, Lins J, Hart AC. Baskoylu SN, et al. Among authors: o hern p. PLoS Genet. 2018 Oct 8;14(10):e1007682. doi: 10.1371/journal.pgen.1007682. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30296255 Free PMC article.
15 results