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The landscape of somatic mutation in normal colorectal epithelial cells.
Lee-Six H, Olafsson S, Ellis P, Osborne RJ, Sanders MA, Moore L, Georgakopoulos N, Torrente F, Noorani A, Goddard M, Robinson P, Coorens THH, O'Neill L, Alder C, Wang J, Fitzgerald RC, Zilbauer M, Coleman N, Saeb-Parsy K, Martincorena I, Campbell PJ, Stratton MR. Lee-Six H, et al. Among authors: alder c. Nature. 2019 Oct;574(7779):532-537. doi: 10.1038/s41586-019-1672-7. Epub 2019 Oct 23. Nature. 2019. PMID: 31645730
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.
Ju YS, Martincorena I, Gerstung M, Petljak M, Alexandrov LB, Rahbari R, Wedge DC, Davies HR, Ramakrishna M, Fullam A, Martin S, Alder C, Patel N, Gamble S, O'Meara S, Giri DD, Sauer T, Pinder SE, Purdie CA, Borg Å, Stunnenberg H, van de Vijver M, Tan BK, Caldas C, Tutt A, Ueno NT, van 't Veer LJ, Martens JW, Sotiriou C, Knappskog S, Span PN, Lakhani SR, Eyfjörd JE, Børresen-Dale AL, Richardson A, Thompson AM, Viari A, Hurles ME, Nik-Zainal S, Campbell PJ, Stratton MR. Ju YS, et al. Among authors: alder c. Nature. 2017 Mar 30;543(7647):714-718. doi: 10.1038/nature21703. Epub 2017 Mar 22. Nature. 2017. PMID: 28329761 Free PMC article.
Intra-tumour diversification in colorectal cancer at the single-cell level.
Roerink SF, Sasaki N, Lee-Six H, Young MD, Alexandrov LB, Behjati S, Mitchell TJ, Grossmann S, Lightfoot H, Egan DA, Pronk A, Smakman N, van Gorp J, Anderson E, Gamble SJ, Alder C, van de Wetering M, Campbell PJ, Stratton MR, Clevers H. Roerink SF, et al. Among authors: alder c. Nature. 2018 Apr;556(7702):457-462. doi: 10.1038/s41586-018-0024-3. Epub 2018 Apr 11. Nature. 2018. PMID: 29643510
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver.
Brunner SF, Roberts ND, Wylie LA, Moore L, Aitken SJ, Davies SE, Sanders MA, Ellis P, Alder C, Hooks Y, Abascal F, Stratton MR, Martincorena I, Hoare M, Campbell PJ. Brunner SF, et al. Among authors: alder c. Nature. 2019 Oct;574(7779):538-542. doi: 10.1038/s41586-019-1670-9. Epub 2019 Oct 23. Nature. 2019. PMID: 31645727 Free PMC article.
Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Snell LB, Alcolea-Medina A, Charalampous T, Alder C, Williams TGS, Flaviani F, Batra R, Bakrania P, Thangarajah R, Neil SJD, van Nispen Tot Pannerden C, Botgros A, Aarons E, Douthwaite ST, Edgeworth JD, Nebbia G. Snell LB, et al. Among authors: alder c. Clin Infect Dis. 2023 Mar 21;76(6):1125-1128. doi: 10.1093/cid/ciac864. Clin Infect Dis. 2023. PMID: 36327795 Free PMC article.
Tissue macrophages and interferon-gamma signalling control blood-stage Plasmodium chabaudi infections derived from mosquito-transmitted parasites.
Deroost K, Alder C, Hosking C, McLaughlin S, Lin JW, Lewis MD, Saavedra-Torres Y, Addy JWG, Levy P, Giorgalli M, Langhorne J. Deroost K, et al. Among authors: alder c. Curr Res Immunol. 2021 Jul 30;2:104-119. doi: 10.1016/j.crimmu.2021.07.002. eCollection 2021. Curr Res Immunol. 2021. PMID: 34532703 Free PMC article.
Analysis of pir gene expression across the Plasmodium life cycle.
Little TS, Cunningham DA, Vandomme A, Lopez CT, Amis S, Alder C, Addy JWG, McLaughlin S, Hosking C, Christophides G, Reid AJ, Langhorne J. Little TS, et al. Among authors: alder c. Malar J. 2021 Nov 25;20(1):445. doi: 10.1186/s12936-021-03979-6. Malar J. 2021. PMID: 34823519 Free PMC article.
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units.
Charalampous T, Alcolea-Medina A, Snell LB, Williams TGS, Batra R, Alder C, Telatin A, Camporota L, Meadows CIS, Wyncoll D, Barrett NA, Hemsley CJ, Bryan L, Newsholme W, Boyd SE, Green A, Mahadeva U, Patel A, Cliff PR, Page AJ, O'Grady J, Edgeworth JD. Charalampous T, et al. Among authors: alder c. Genome Med. 2021 Nov 17;13(1):182. doi: 10.1186/s13073-021-00991-y. Genome Med. 2021. PMID: 34784976 Free PMC article.
47 results