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Building better enzymes: Molecular basis of improved non-natural nucleobase incorporation by an evolved DNA polymerase.
Protein Sci. 2020 Feb;29(2):455-468. doi: 10.1002/pro.3762. Epub 2019 Nov 14.
Protein Sci. 2020.
PMID: 31654473
Free PMC article.
Building better polymerases: Engineering the replication of expanded genetic alphabets.
Ouaray Z, Benner SA, Georgiadis MM, Richards NGJ.
Ouaray Z, et al.
J Biol Chem. 2020 Dec 11;295(50):17046-17059. doi: 10.1074/jbc.REV120.013745. Epub 2020 Oct 1.
J Biol Chem. 2020.
PMID: 33004440
Free PMC article.
Review.
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Reactivation of mutant p53: Constraints on mechanism highlighted by principal component analysis of the DNA binding domain.
Ouaray Z, ElSawy KM, Lane DP, Essex JW, Verma C.
Ouaray Z, et al.
Proteins. 2016 Oct;84(10):1443-61. doi: 10.1002/prot.25089. Epub 2016 Jul 26.
Proteins. 2016.
PMID: 27317883
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Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket.
Pradhan MR, Siau JW, Kannan S, Nguyen MN, Ouaray Z, Kwoh CK, Lane DP, Ghadessy F, Verma CS.
Pradhan MR, et al. Among authors: ouaray z.
Nucleic Acids Res. 2019 Feb 28;47(4):1637-1652. doi: 10.1093/nar/gky1314.
Nucleic Acids Res. 2019.
PMID: 30649466
Free PMC article.
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The Multifaceted Roles of Molecular Dynamics Simulations in Drug Discovery.
Fox SJ, Li J, Tan YS, Nguyen MN, Pal A, Ouaray Z, Yadahalli S, Kannan S.
Fox SJ, et al. Among authors: ouaray z.
Curr Pharm Des. 2016;22(23):3585-600. doi: 10.2174/1381612822666160425120507.
Curr Pharm Des. 2016.
PMID: 27108593
Review.
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