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USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection.
Dagenais-Lussier X, Loucif H, Cadorel H, Blumberger J, Isnard S, Bego MG, Cohen ÉA, Routy JP, van Grevenynghe J; Montreal Primary Infection Study Group. Dagenais-Lussier X, et al. Among authors: van grevenynghe j. PLoS Pathog. 2019 Oct 28;15(10):e1008060. doi: 10.1371/journal.ppat.1008060. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31658294 Free PMC article.
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.
Riou C, Yassine-Diab B, Van grevenynghe J, Somogyi R, Greller LD, Gagnon D, Gimmig S, Wilkinson P, Shi Y, Cameron MJ, Campos-Gonzalez R, Balderas RS, Kelvin D, Sekaly RP, Haddad EK. Riou C, et al. Among authors: van grevenynghe j. J Exp Med. 2007 Jan 22;204(1):79-91. doi: 10.1084/jem.20061681. Epub 2006 Dec 26. J Exp Med. 2007. PMID: 17190839 Free PMC article.
T-cell exhaustion in HIV infection.
El-Far M, Halwani R, Said E, Trautmann L, Doroudchi M, Janbazian L, Fonseca S, van Grevenynghe J, Yassine-Diab B, Sékaly RP, Haddad EK. El-Far M, et al. Among authors: van grevenynghe j. Curr HIV/AIDS Rep. 2008 Feb;5(1):13-9. doi: 10.1007/s11904-008-0003-7. Curr HIV/AIDS Rep. 2008. PMID: 18417030 Review.
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.
Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, El-Far M, Hill BJ, Noto A, Ancuta P, Peretz Y, Fonseca SG, Van Grevenynghe J, Boulassel MR, Bruneau J, Shoukry NH, Routy JP, Douek DC, Haddad EK, Sekaly RP. Said EA, et al. Among authors: van grevenynghe j. Nat Med. 2010 Apr;16(4):452-9. doi: 10.1038/nm.2106. Epub 2010 Mar 7. Nat Med. 2010. PMID: 20208540 Free PMC article.
Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.
van Grevenynghe J, Cubas RA, Noto A, DaFonseca S, He Z, Peretz Y, Filali-Mouhim A, Dupuy FP, Procopio FA, Chomont N, Balderas RS, Said EA, Boulassel MR, Tremblay CL, Routy JP, Sékaly RP, Haddad EK. van Grevenynghe J, et al. J Clin Invest. 2011 Oct;121(10):3877-88. doi: 10.1172/JCI59211. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926463 Free PMC article.
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection.
Trautmann L, Mbitikon-Kobo FM, Goulet JP, Peretz Y, Shi Y, Van Grevenynghe J, Procopio FA, Boulassel MR, Routy JP, Chomont N, Haddad EK, Sekaly RP. Trautmann L, et al. Among authors: van grevenynghe j. Blood. 2012 Oct 25;120(17):3466-77. doi: 10.1182/blood-2012-04-422550. Epub 2012 Sep 6. Blood. 2012. PMID: 22955926 Free PMC article.
Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.
El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, Chomont N, Sékaly RP. El-Far M, et al. Among authors: van grevenynghe j. J Gen Virol. 2015 Jun;96(Pt 6):1463-1477. doi: 10.1099/vir.0.000065. Epub 2015 Jan 27. J Gen Virol. 2015. PMID: 25626682 Free PMC article.
Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F, He Z, Metcalf T, Ghneim K, Locci M, Ancuta P, Routy JP, Trautmann L, Li Y, McDermott AB, Koup RA, Petrovas C, Migueles SA, Connors M, Tomaras GD, Moir S, Crotty S, Haddad EK. Cubas R, et al. Among authors: van grevenynghe j. J Immunol. 2015 Dec 15;195(12):5625-36. doi: 10.4049/jimmunol.1501524. Epub 2015 Nov 6. J Immunol. 2015. PMID: 26546609 Free PMC article.
41 results