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N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
Juin A, Spence HJ, Martin KJ, McGhee E, Neilson M, Cutiongco MFA, Gadegaard N, Mackay G, Fort L, Lilla S, Kalna G, Thomason P, Koh YWH, Norman JC, Insall RH, Machesky LM. Juin A, et al. Among authors: mcghee e. Dev Cell. 2019 Nov 18;51(4):431-445.e7. doi: 10.1016/j.devcel.2019.09.018. Epub 2019 Oct 24. Dev Cell. 2019. PMID: 31668663 Free PMC article.
ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Myant KB, Cammareri P, McGhee EJ, Ridgway RA, Huels DJ, Cordero JB, Schwitalla S, Kalna G, Ogg EL, Athineos D, Timpson P, Vidal M, Murray GI, Greten FR, Anderson KI, Sansom OJ. Myant KB, et al. Cell Stem Cell. 2013 Jun 6;12(6):761-73. doi: 10.1016/j.stem.2013.04.006. Epub 2013 May 9. Cell Stem Cell. 2013. PMID: 23665120 Free PMC article.
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.
Reid SE, Kay EJ, Neilson LJ, Henze AT, Serneels J, McGhee EJ, Dhayade S, Nixon C, Mackey JB, Santi A, Swaminathan K, Athineos D, Papalazarou V, Patella F, Román-Fernández Á, ElMaghloob Y, Hernandez-Fernaud JR, Adams RH, Ismail S, Bryant DM, Salmeron-Sanchez M, Machesky LM, Carlin LM, Blyth K, Mazzone M, Zanivan S. Reid SE, et al. Among authors: mcghee ej. EMBO J. 2017 Aug 15;36(16):2373-2389. doi: 10.15252/embj.201694912. Epub 2017 Jul 10. EMBO J. 2017. PMID: 28694244 Free PMC article.
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
Novo D, Heath N, Mitchell L, Caligiuri G, MacFarlane A, Reijmer D, Charlton L, Knight J, Calka M, McGhee E, Dornier E, Sumpton D, Mason S, Echard A, Klinkert K, Secklehner J, Kruiswijk F, Vousden K, Macpherson IR, Blyth K, Bailey P, Yin H, Carlin LM, Morton J, Zanivan S, Norman JC. Novo D, et al. Among authors: mcghee e. Nat Commun. 2018 Nov 29;9(1):5069. doi: 10.1038/s41467-018-07339-y. Nat Commun. 2018. PMID: 30498210 Free PMC article.
A RAC-GEF network critical for early intestinal tumourigenesis.
Pickering KA, Gilroy K, Cassidy JW, Fey SK, Najumudeen AK, Zeiger LB, Vincent DF, Gay DM, Johansson J, Fordham RP, Miller B, Clark W, Hedley A, Unal EB, Kiel C, McGhee E, Machesky LM, Nixon C, Johnsson AE, Bain M, Strathdee D, van Hoof SR, Medema JP, Anderson KI, Brachmann SM, Stucke VM, Malliri A, Drysdale M, Turner M, Serrano L, Myant K, Campbell AD, Sansom OJ. Pickering KA, et al. Among authors: mcghee e. Nat Commun. 2021 Jan 4;12(1):56. doi: 10.1038/s41467-020-20255-4. Nat Commun. 2021. PMID: 33397922 Free PMC article.
Single-sample image-fusion upsampling of fluorescence lifetime images.
Kapitany V, Fatima A, Zickus V, Whitelaw J, McGhee E, Insall R, Machesky L, Faccio D. Kapitany V, et al. Among authors: mcghee e. Sci Adv. 2024 May 24;10(21):eadn0139. doi: 10.1126/sciadv.adn0139. Epub 2024 May 23. Sci Adv. 2024. PMID: 38781345 Free PMC article.
68 results