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The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors.
Luo XJ, Li M, Huang L, Nho K, Deng M, Chen Q, Weinberger DR, Vasquez AA, Rijpkema M, Mattay VS, Saykin AJ, Shen L, Fernández G, Franke B, Chen JC, Chen XN, Wang JK, Xiao X, Qi XB, Xiang K, Peng YM, Cao XY, Li Y, Shi XD; Alzheimer’s Disease Neuroimaging Initiative; Gan L, Su B. Luo XJ, et al. Among authors: xiao x. PLoS One. 2012;7(11):e50375. doi: 10.1371/journal.pone.0050375. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226269 Free PMC article.
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
Benyamin B, Pourcain B, Davis OS, Davies G, Hansell NK, Brion MJ, Kirkpatrick RM, Cents RA, Franić S, Miller MB, Haworth CM, Meaburn E, Price TS, Evans DM, Timpson N, Kemp J, Ring S, McArdle W, Medland SE, Yang J, Harris SE, Liewald DC, Scheet P, Xiao X, Hudziak JJ, de Geus EJ; Wellcome Trust Case Control Consortium 2 (WTCCC2); Jaddoe VW, Starr JM, Verhulst FC, Pennell C, Tiemeier H, Iacono WG, Palmer LJ, Montgomery GW, Martin NG, Boomsma DI, Posthuma D, McGue M, Wright MJ, Davey Smith G, Deary IJ, Plomin R, Visscher PM. Benyamin B, et al. Among authors: xiao x. Mol Psychiatry. 2014 Feb;19(2):253-8. doi: 10.1038/mp.2012.184. Epub 2013 Jan 29. Mol Psychiatry. 2014. PMID: 23358156 Free PMC article.
Further evidence of VRK2 rs2312147 associated with schizophrenia.
Chang H, Zhang C, Xiao X, Pu X, Liu Z, Wu L, Li M. Chang H, et al. Among authors: xiao x. World J Biol Psychiatry. 2016 Sep;17(6):457-66. doi: 10.1080/15622975.2016.1200746. Epub 2016 Jul 6. World J Biol Psychiatry. 2016. PMID: 27382989
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