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Rapid stromal remodeling by short-term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma.
Steins A, Klaassen R, Jacobs I, Schabel MC, van Lier MGJTB, Ebbing EA, Hectors SJ, Tas SW, Maracle CX, Punt CJA, Siebes M, Bergman JJGHM, Medema JP, Wilmink JW, Mathot RAA, Strijkers GJ, Bijlsma MF, van Laarhoven HWM. Steins A, et al. Among authors: ebbing ea. Mol Oncol. 2020 Apr;14(4):704-720. doi: 10.1002/1878-0261.12599. Epub 2020 Mar 3. Mol Oncol. 2020. PMID: 31733011 Free PMC article.
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma.
Ebbing EA, van der Zalm AP, Steins A, Creemers A, Hermsen S, Rentenaar R, Klein M, Waasdorp C, Hooijer GKJ, Meijer SL, Krishnadath KK, Punt CJA, van Berge Henegouwen MI, Gisbertz SS, van Delden OM, Hulshof MCCM, Medema JP, van Laarhoven HWM, Bijlsma MF. Ebbing EA, et al. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2237-2242. doi: 10.1073/pnas.1820459116. Epub 2019 Jan 22. Proc Natl Acad Sci U S A. 2019. PMID: 30670657 Free PMC article.
Chemoradiation induces epithelial-to-mesenchymal transition in esophageal adenocarcinoma.
Steins A, Ebbing EA, Creemers A, van der Zalm AP, Jibodh RA, Waasdorp C, Meijer SL, van Delden OM, Krishnadath KK, Hulshof MCCM, Bennink RJ, Punt CJA, Medema JP, Bijlsma MF, van Laarhoven HWM. Steins A, et al. Among authors: ebbing ea. Int J Cancer. 2019 Nov 15;145(10):2792-2803. doi: 10.1002/ijc.32364. Epub 2019 May 7. Int J Cancer. 2019. PMID: 31018252 Free PMC article.
FOXO transcriptional activity is associated with response to chemoradiation in EAC.
Creemers A, van der Zalm AP, van de Stolpe A, Holtzer L, Stoffels M, Hooijer GKJ, Ebbing EA, van Ooijen H, van Brussel AGC, Aussems-Custers EMG, van Berge Henegouwen MI, Hulshof MCCM, Bergman JJGHM, Meijer SL, Bijlsma MF, van Laarhoven HWM. Creemers A, et al. Among authors: ebbing ea. J Transl Med. 2022 Apr 25;20(1):183. doi: 10.1186/s12967-022-03376-w. J Transl Med. 2022. PMID: 35468793 Free PMC article.
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Ebbing EA, Steins A, Fessler E, Stathi P, Lesterhuis WJ, Krishnadath KK, Vermeulen L, Medema JP, Bijlsma MF, van Laarhoven HWM. Ebbing EA, et al. Gastroenterology. 2017 Jul;153(1):63-76.e14. doi: 10.1053/j.gastro.2017.03.004. Epub 2017 Mar 9. Gastroenterology. 2017. PMID: 28286209
The dynamics of HER2 status in esophageal adenocarcinoma.
Creemers A, Ebbing EA, Hooijer GKJ, Stap L, Jibodh-Mulder RA, Gisbertz SS, van Berge Henegouwen MI, van Montfoort ML, Hulshof MCCM, Krishnadath KK, van Oijen MGH, Bijlsma MF, Meijer SL, van Laarhoven HWM. Creemers A, et al. Among authors: ebbing ea. Oncotarget. 2018 Jun 1;9(42):26787-26799. doi: 10.18632/oncotarget.25507. eCollection 2018 Jun 1. Oncotarget. 2018. PMID: 29928485 Free PMC article.
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract.
Damhofer H, Ebbing EA, Steins A, Welling L, Tol JA, Krishnadath KK, van Leusden T, van de Vijver MJ, Besselink MG, Busch OR, van Berge Henegouwen MI, van Delden O, Meijer SL, Dijk F, Medema JP, van Laarhoven HW, Bijlsma MF. Damhofer H, et al. Among authors: ebbing ea. J Transl Med. 2015 Apr 11;13:115. doi: 10.1186/s12967-015-0469-1. J Transl Med. 2015. PMID: 25884700 Free PMC article.
12 results