Kortemme T - Search Results

1

Computational design of a modular protein sense-response system.

Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. Glasgow AA, et al. Among authors: kortemme t. Science. 2019 Nov 22;366(6468):1024-1028. doi: 10.1126/science.aax8780. Science. 2019. PMID: 31754004 Free PMC article.

2

Design of multi-specificity in protein interfaces.

Humphris EL, Kortemme T. Humphris EL, et al. Among authors: kortemme t. PLoS Comput Biol. 2007 Aug;3(8):e164. doi: 10.1371/journal.pcbi.0030164. Epub 2007 Jul 5. PLoS Comput Biol. 2007. PMID: 17722975 Free PMC article.

3

Prediction of protein-protein interface sequence diversity using flexible backbone computational protein design.

Humphris EL, Kortemme T. Humphris EL, et al. Among authors: kortemme t. Structure. 2008 Dec 10;16(12):1777-88. doi: 10.1016/j.str.2008.09.012. Structure. 2008. PMID: 19081054 Free article.

4

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling.

Mandell DJ, Coutsias EA, Kortemme T. Mandell DJ, et al. Among authors: kortemme t. Nat Methods. 2009 Aug;6(8):551-2. doi: 10.1038/nmeth0809-551. Nat Methods. 2009. PMID: 19644455 Free PMC article. No abstract available.

5

Backbone flexibility in computational protein design.

Mandell DJ, Kortemme T. Mandell DJ, et al. Among authors: kortemme t. Curr Opin Biotechnol. 2009 Aug;20(4):420-8. doi: 10.1016/j.copbio.2009.07.006. Epub 2009 Aug 24. Curr Opin Biotechnol. 2009. PMID: 19709874 Review.

6

Computer-aided design of functional protein interactions.

Mandell DJ, Kortemme T. Mandell DJ, et al. Among authors: kortemme t. Nat Chem Biol. 2009 Nov;5(11):797-807. doi: 10.1038/nchembio.251. Nat Chem Biol. 2009. PMID: 19841629 Review.

7

Assessment of flexible backbone protein design methods for sequence library prediction in the therapeutic antibody Herceptin-HER2 interface.

Babor M, Mandell DJ, Kortemme T. Babor M, et al. Among authors: kortemme t. Protein Sci. 2011 Jun;20(6):1082-9. doi: 10.1002/pro.632. Epub 2011 May 3. Protein Sci. 2011. PMID: 21465611 Free PMC article.

8

A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme.

Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J. Chao LH, et al. Among authors: kortemme t. Cell. 2011 Sep 2;146(5):732-45. doi: 10.1016/j.cell.2011.07.038. Cell. 2011. PMID: 21884935 Free PMC article.

9

Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.

Kapp GT, Liu S, Stein A, Wong DT, Reményi A, Yeh BJ, Fraser JS, Taunton J, Lim WA, Kortemme T. Kapp GT, et al. Among authors: kortemme t. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5277-82. doi: 10.1073/pnas.1114487109. Epub 2012 Mar 7. Proc Natl Acad Sci U S A. 2012. PMID: 22403064 Free PMC article.

10

Cost-benefit tradeoffs in engineered lac operons.

Eames M, Kortemme T. Eames M, et al. Among authors: kortemme t. Science. 2012 May 18;336(6083):911-5. doi: 10.1126/science.1219083. Science. 2012. PMID: 22605776

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