Pache RA - Search Results

1

Computational design of a modular protein sense-response system.

Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. Glasgow AA, et al. Among authors: pache ra. Science. 2019 Nov 22;366(6468):1024-1028. doi: 10.1126/science.aax8780. Science. 2019. PMID: 31754004 Free PMC article.

2

Accurate positioning of functional residues with robotics-inspired computational protein design.

Krivacic C, Kundert K, Pan X, Pache RA, Liu L, Conchúir SO, Jeliazkov JR, Gray JJ, Thompson MC, Fraser JS, Kortemme T. Krivacic C, et al. Among authors: pache ra. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2115480119. doi: 10.1073/pnas.2115480119. Epub 2022 Mar 7. Proc Natl Acad Sci U S A. 2022. PMID: 35254891 Free PMC article.

3

A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design.

Ó Conchúir S, Barlow KA, Pache RA, Ollikainen N, Kundert K, O'Meara MJ, Smith CA, Kortemme T. Ó Conchúir S, et al. Among authors: pache ra. PLoS One. 2015 Sep 3;10(9):e0130433. doi: 10.1371/journal.pone.0130433. eCollection 2015. PLoS One. 2015. PMID: 26335248 Free PMC article.

4

Engineering a light-activated caspase-3 for precise ablation of neurons in vivo.

Smart AD, Pache RA, Thomsen ND, Kortemme T, Davis GW, Wells JA. Smart AD, et al. Among authors: pache ra. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8174-E8183. doi: 10.1073/pnas.1705064114. Epub 2017 Sep 11. Proc Natl Acad Sci U S A. 2017. PMID: 28893998 Free PMC article.

5

Scientific benchmarks for guiding macromolecular energy function improvement.

Leaver-Fay A, O'Meara MJ, Tyka M, Jacak R, Song Y, Kellogg EH, Thompson J, Davis IW, Pache RA, Lyskov S, Gray JJ, Kortemme T, Richardson JS, Havranek JJ, Snoeyink J, Baker D, Kuhlman B. Leaver-Fay A, et al. Among authors: pache ra. Methods Enzymol. 2013;523:109-43. doi: 10.1016/B978-0-12-394292-0.00006-0. Methods Enzymol. 2013. PMID: 23422428 Free PMC article.

6

A novel framework for the comparative analysis of biological networks.

Pache RA, Aloy P. Pache RA, et al. PLoS One. 2012;7(2):e31220. doi: 10.1371/journal.pone.0031220. Epub 2012 Feb 21. PLoS One. 2012. PMID: 22363585 Free PMC article.

7

Dynamic interactions of proteins in complex networks: a more structured view.

Stein A, Pache RA, Bernadó P, Pons M, Aloy P. Stein A, et al. Among authors: pache ra. FEBS J. 2009 Oct;276(19):5390-405. doi: 10.1111/j.1742-4658.2009.07251.x. Epub 2009 Aug 27. FEBS J. 2009. PMID: 19712106 Free article. Review.

8

The role of structural disorder in the rewiring of protein interactions through evolution.

Mosca R, Pache RA, Aloy P. Mosca R, et al. Among authors: pache ra. Mol Cell Proteomics. 2012 Jul;11(7):M111.014969. doi: 10.1074/mcp.M111.014969. Epub 2012 Mar 2. Mol Cell Proteomics. 2012. PMID: 22389433 Free PMC article.

9

Incorporating high-throughput proteomics experiments into structural biology pipelines: identification of the low-hanging fruits.

Pache RA, Aloy P. Pache RA, et al. Proteomics. 2008 May;8(10):1959-64. doi: 10.1002/pmic.200700966. Proteomics. 2008. PMID: 18491310

10

Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions.

Pache RA, Babu MM, Aloy P. Pache RA, et al. BMC Syst Biol. 2009 Jul 18;3:74. doi: 10.1186/1752-0509-3-74. BMC Syst Biol. 2009. PMID: 19615085 Free PMC article.

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