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Deep diversification of an AAV capsid protein by machine learning.
Bryant DH, Bashir A, Sinai S, Jain NK, Ogden PJ, Riley PF, Church GM, Colwell LJ, Kelsic ED. Bryant DH, et al. Among authors: sinai s. Nat Biotechnol. 2021 Jun;39(6):691-696. doi: 10.1038/s41587-020-00793-4. Epub 2021 Feb 11. Nat Biotechnol. 2021. PMID: 33574611
Protein design using structure-based residue preferences.
Ding D, Shaw AY, Sinai S, Rollins N, Prywes N, Savage DF, Laub MT, Marks DS. Ding D, et al. Among authors: sinai s. Nat Commun. 2024 Feb 22;15(1):1639. doi: 10.1038/s41467-024-45621-4. Nat Commun. 2024. PMID: 38388493 Free PMC article.
Primordial sex facilitates the emergence of evolution.
Sinai S, Olejarz J, Neagu IA, Nowak MA. Sinai S, et al. J R Soc Interface. 2018 Feb;15(139):20180003. doi: 10.1098/rsif.2018.0003. J R Soc Interface. 2018. PMID: 29491181 Free PMC article.
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium; Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J. Menden MP, et al. Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2. Nat Commun. 2019. PMID: 31209238 Free PMC article.
17 results