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It's more than low BMI: prevalence of cachexia and associated mortality in COPD.
McDonald MN, Wouters EFM, Rutten E, Casaburi R, Rennard SI, Lomas DA, Bamman M, Celli B, Agusti A, Tal-Singer R, Hersh CP, Dransfield M, Silverman EK. McDonald MN, et al. Respir Res. 2019 May 22;20(1):100. doi: 10.1186/s12931-019-1073-3. Respir Res. 2019. PMID: 31118043 Free PMC article.
Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.
Lakshman Kumar P, Wilson AC, Rocco A, Cho MH, Wan E, Hobbs BD, Washko GR, Ortega VE, Christenson SA, Li X, Wells JM, Bhatt SP, DeMeo DL, Lutz SM, Rossiter H, Casaburi R, Rennard SI, Lomas DA, Labaki WW, Tal-Singer R, Bowler RP, Hersh CP, Tiwari HK, Dransfield M, Thalacker-Mercer A, Meyers DA, Silverman EK, McDonald MN; COPDGene, ECLIPSE and SPIROMICS investigators. Lakshman Kumar P, et al. Among authors: mcdonald mn. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1803-1817. doi: 10.1002/jcsm.12782. Epub 2021 Sep 15. J Cachexia Sarcopenia Muscle. 2021. PMID: 34523824 Free PMC article.
Novel genetic loci associated with osteoarthritis in multi-ancestry analyses in the Million Veteran Program and UK Biobank.
McDonald MN, Lakshman Kumar P, Srinivasasainagendra V, Nair A, Rocco AP, Wilson AC, Chiles JW, Richman JS, Pinson SA, Dennis RA, Jagadale V, Brown CJ, Pyarajan S, Tiwari HK, Bamman MM, Singh JA. McDonald MN, et al. Nat Genet. 2022 Dec;54(12):1816-1826. doi: 10.1038/s41588-022-01221-w. Epub 2022 Nov 21. Nat Genet. 2022. PMID: 36411363
Differentially co-expressed myofibre transcripts associated with abnormal myofibre proportion in chronic obstructive pulmonary disease.
Chiles JW 3rd, Wilson AC, Tindal R, Lavin K, Windham S, Rossiter HB, Casaburi R, Thalacker-Mercer A, Buford TW, Patel R, Wells JM, Bamman MM, Hanaoka BY, Dransfield M, McDonald MN. Chiles JW 3rd, et al. Among authors: mcdonald mn. J Cachexia Sarcopenia Muscle. 2024 Apr 22. doi: 10.1002/jcsm.13473. Online ahead of print. J Cachexia Sarcopenia Muscle. 2024. PMID: 38649783 Free article.
Heme metabolism genes Downregulated in COPD Cachexia.
Wilson AC, Kumar PL, Lee S, Parker MM, Arora I, Morrow JD, Wouters EFM, Casaburi R, Rennard SI, Lomas DA, Agusti A, Tal-Singer R, Dransfield MT, Wells JM, Bhatt SP, Washko G, Thannickal VJ, Tiwari HK, Hersh CP, Castaldi PJ, Silverman EK, McDonald MN. Wilson AC, et al. Among authors: mcdonald mn. Respir Res. 2020 May 1;21(1):100. doi: 10.1186/s12931-020-01336-w. Respir Res. 2020. PMID: 32354332 Free PMC article.
Respiratory exacerbations are associated with muscle loss in current and former smokers.
Mason SE, Moreta-Martinez R, Labaki WW, Strand M, Baraghoshi D, Regan EA, Bon J, San Jose Estepar R, Casaburi R, McDonald MN, Rossiter H, Make BJ, Dransfield MT, Han MK, Young KA, Kinney G, Hokanson JE, San Jose Estepar R, Washko GR; COPDGene Investigators; COPDGene® Investigators. Mason SE, et al. Among authors: mcdonald mn. Thorax. 2021 Jun;76(6):554-560. doi: 10.1136/thoraxjnl-2020-215999. Epub 2021 Feb 11. Thorax. 2021. PMID: 33574123 Free PMC article.
39 results