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High-Throughput Generation of Bispecific Binding Proteins by Sortase A-Mediated Coupling for Direct Functional Screening in Cell Culture.
Mol Cancer Ther. 2020 Apr;19(4):1080-1088. doi: 10.1158/1535-7163.MCT-19-0633. Epub 2019 Dec 23.
Mol Cancer Ther. 2020.
PMID: 31871271
Designed ankyrin repeat proteins (DARPins) from research to therapy.
Tamaskovic R, Simon M, Stefan N, Schwill M, Plückthun A.
Tamaskovic R, et al. Among authors: schwill m.
Methods Enzymol. 2012;503:101-34. doi: 10.1016/B978-0-12-396962-0.00005-7.
Methods Enzymol. 2012.
PMID: 22230567
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Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2.
Jost C, Schilling J, Tamaskovic R, Schwill M, Honegger A, Plückthun A.
Jost C, et al. Among authors: schwill m.
Structure. 2013 Nov 5;21(11):1979-91. doi: 10.1016/j.str.2013.08.020. Epub 2013 Oct 3.
Structure. 2013.
PMID: 24095059
Free article.
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Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk.
Tamaskovic R, Schwill M, Nagy-Davidescu G, Jost C, Schaefer DC, Verdurmen WP, Schaefer JV, Honegger A, Plückthun A.
Tamaskovic R, et al. Among authors: schwill m.
Nat Commun. 2016 Jun 3;7:11672. doi: 10.1038/ncomms11672.
Nat Commun. 2016.
PMID: 27255951
Free PMC article.
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Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization.
Stüber JC, Richter CP, Bellón JS, Schwill M, König I, Schuler B, Piehler J, Plückthun A.
Stüber JC, et al. Among authors: schwill m.
Commun Biol. 2021 Jun 21;4(1):762. doi: 10.1038/s42003-021-02253-4.
Commun Biol. 2021.
PMID: 34155320
Free PMC article.
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Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer.
Schwill M, Tamaskovic R, Gajadhar AS, Kast F, White FM, Plückthun A.
Schwill M, et al.
Sci Signal. 2019 Jan 22;12(565):eaau2875. doi: 10.1126/scisignal.aau2875.
Sci Signal. 2019.
PMID: 30670633
Free PMC article.
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Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A.
Kast F, et al. Among authors: schwill m.
Nat Commun. 2021 Jun 18;12(1):3790. doi: 10.1038/s41467-021-23948-6.
Nat Commun. 2021.
PMID: 34145240
Free PMC article.
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