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The circadian clock protein REVERBα inhibits pulmonary fibrosis development.
Cunningham PS, Meijer P, Nazgiewicz A, Anderson SG, Borthwick LA, Bagnall J, Kitchen GB, Lodyga M, Begley N, Venkateswaran RV, Shah R, Mercer PF, Durrington HJ, Henderson NC, Piper-Hanley K, Fisher AJ, Chambers RC, Bechtold DA, Gibbs JE, Loudon AS, Rutter MK, Hinz B, Ray DW, Blaikley JF. Cunningham PS, et al. Among authors: chambers rc. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1139-1147. doi: 10.1073/pnas.1912109117. Epub 2019 Dec 26. Proc Natl Acad Sci U S A. 2020. PMID: 31879343 Free PMC article.
Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.
Mercer PF, Johns RH, Scotton CJ, Krupiczojc MA, Königshoff M, Howell DC, McAnulty RJ, Das A, Thorley AJ, Tetley TD, Eickelberg O, Chambers RC. Mercer PF, et al. Among authors: chambers rc. Am J Respir Crit Care Med. 2009 Mar 1;179(5):414-25. doi: 10.1164/rccm.200712-1827OC. Epub 2008 Dec 5. Am J Respir Crit Care Med. 2009. PMID: 19060230 Free PMC article.
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.
Scotton CJ, Krupiczojc MA, Königshoff M, Mercer PF, Lee YC, Kaminski N, Morser J, Post JM, Maher TM, Nicholson AG, Moffatt JD, Laurent GJ, Derian CK, Eickelberg O, Chambers RC. Scotton CJ, et al. Among authors: chambers rc. J Clin Invest. 2009 Sep;119(9):2550-63. doi: 10.1172/JCI33288. Epub 2009 Aug 3. J Clin Invest. 2009. PMID: 19652365 Free PMC article.
Novel therapeutic approaches for pulmonary fibrosis.
Datta A, Scotton CJ, Chambers RC. Datta A, et al. Among authors: chambers rc. Br J Pharmacol. 2011 May;163(1):141-72. doi: 10.1111/j.1476-5381.2011.01247.x. Br J Pharmacol. 2011. PMID: 21265830 Free PMC article. Review.
Coagulation and coagulation signalling in fibrosis.
Mercer PF, Chambers RC. Mercer PF, et al. Among authors: chambers rc. Biochim Biophys Acta. 2013 Jul;1832(7):1018-27. doi: 10.1016/j.bbadis.2012.12.013. Epub 2013 Jan 5. Biochim Biophys Acta. 2013. PMID: 23298546 Free article. Review.
149 results