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The circadian clock protein REVERBα inhibits pulmonary fibrosis development.
Cunningham PS, Meijer P, Nazgiewicz A, Anderson SG, Borthwick LA, Bagnall J, Kitchen GB, Lodyga M, Begley N, Venkateswaran RV, Shah R, Mercer PF, Durrington HJ, Henderson NC, Piper-Hanley K, Fisher AJ, Chambers RC, Bechtold DA, Gibbs JE, Loudon AS, Rutter MK, Hinz B, Ray DW, Blaikley JF. Cunningham PS, et al. Among authors: mercer pf. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1139-1147. doi: 10.1073/pnas.1912109117. Epub 2019 Dec 26. Proc Natl Acad Sci U S A. 2020. PMID: 31879343 Free PMC article.
Mechanisms of alveolar epithelial injury, repair, and fibrosis.
Chambers RC, Mercer PF. Chambers RC, et al. Among authors: mercer pf. Ann Am Thorac Soc. 2015 Mar;12 Suppl 1(Suppl 1):S16-20. doi: 10.1513/AnnalsATS.201410-448MG. Ann Am Thorac Soc. 2015. PMID: 25830828 Free PMC article. Review.
Coagulation and coagulation signalling in fibrosis.
Mercer PF, Chambers RC. Mercer PF, et al. Biochim Biophys Acta. 2013 Jul;1832(7):1018-27. doi: 10.1016/j.bbadis.2012.12.013. Epub 2013 Jan 5. Biochim Biophys Acta. 2013. PMID: 23298546 Free article. Review.
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
John AE, Graves RH, Pun KT, Vitulli G, Forty EJ, Mercer PF, Morrell JL, Barrett JW, Rogers RF, Hafeji M, Bibby LI, Gower E, Morrison VS, Man Y, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Le J, Flint DJ, Pyne S, Habgood A, Organ LA, Joseph C, Edwards-Pritchard RC, Maher TM, Fisher AJ, Gudmann NS, Leeming DJ, Chambers RC, Lukey PT, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. John AE, et al. Among authors: mercer pf. Nat Commun. 2020 Sep 16;11(1):4659. doi: 10.1038/s41467-020-18397-6. Nat Commun. 2020. PMID: 32938936 Free PMC article.
The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection.
Smoktunowicz N, Alexander RE, Franklin L, Williams AE, Holman B, Mercer PF, Jarai G, Scotton CJ, Chambers RC. Smoktunowicz N, et al. Among authors: mercer pf. Dis Model Mech. 2015 Sep;8(9):1129-39. doi: 10.1242/dmm.019984. Epub 2015 Jul 2. Dis Model Mech. 2015. PMID: 26138704 Free PMC article.
57 results