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Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes.
Liu Y, Bunney TD, Khosa S, Macé K, Beckenbauer K, Askwith T, Maslen S, Stubbs C, de Oliveira TM, Sader K, Skehel M, Gavin AC, Phillips C, Katan M. Liu Y, et al. Among authors: maslen s. EBioMedicine. 2020 Jan;51:102607. doi: 10.1016/j.ebiom.2019.102607. Epub 2020 Jan 6. EBioMedicine. 2020. PMID: 31918402 Free PMC article.
Molecular mechanism of APC/C activation by mitotic phosphorylation.
Zhang S, Chang L, Alfieri C, Zhang Z, Yang J, Maslen S, Skehel M, Barford D. Zhang S, et al. Among authors: maslen s. Nature. 2016 May 12;533(7602):260-264. doi: 10.1038/nature17973. Epub 2016 Apr 27. Nature. 2016. PMID: 27120157 Free PMC article.
Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.
Hill CH, Boreikaitė V, Kumar A, Casañal A, Kubík P, Degliesposti G, Maslen S, Mariani A, von Loeffelholz O, Girbig M, Skehel M, Passmore LA. Hill CH, et al. Among authors: maslen s. Mol Cell. 2019 Mar 21;73(6):1217-1231.e11. doi: 10.1016/j.molcel.2018.12.023. Epub 2019 Feb 5. Mol Cell. 2019. PMID: 30737185 Free PMC article.
83 results