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VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis.
Low S, Wu H, Jerath K, Tibolla A, Fogal B, Conrad R, MacDougall M, Kerr S, Berger V, Dave R, Villalona J, Pantages L, Ahlberg J, Li H, Van Hoorick D, Ververken C, Broadwater J, Waterman A, Singh S, Kroe-Barrett R. Low S, et al. Among authors: jerath k. MAbs. 2020 Jan-Dec;12(1):1709322. doi: 10.1080/19420862.2019.1709322. MAbs. 2020. PMID: 31924119 Free PMC article.
Non-neutralizing antibodies increase endogenous circulating Ang1 levels.
Zheng C, Toth J, Bigwarfe T, MacDougall M, Jerath K, Bovat K, Smith J, Sun P, Hayes D, Fryer R, Singh S, Kroe-Barrett R. Zheng C, et al. Among authors: jerath k. MAbs. 2018 Nov-Dec;10(8):1260-1268. doi: 10.1080/19420862.2018.1521130. Epub 2018 Nov 7. MAbs. 2018. PMID: 30199300 Free PMC article.
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.
Ganesan R, Raymond EL, Mennerich D, Woska JR Jr, Caviness G, Grimaldi C, Ahlberg J, Perez R, Roberts S, Yang D, Jerath K, Truncali K, Frego L, Sepulveda E, Gupta P, Brown SE, Howell MD, Canada KA, Kroe-Barrett R, Fine JS, Singh S, Mbow ML. Ganesan R, et al. Among authors: jerath k. MAbs. 2017 Oct;9(7):1143-1154. doi: 10.1080/19420862.2017.1353853. Epub 2017 Jul 20. MAbs. 2017. PMID: 28726542 Free PMC article.
Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies.
Venkataramani S, Low S, Weigle B, Dutcher D, Jerath K, Menzenski M, Frego L, Truncali K, Gupta P, Kroe-Barrett R, Ganesan R, Singh S, Erb KJ. Venkataramani S, et al. Among authors: jerath k. Biochem Biophys Res Commun. 2018 Sep 26;504(1):19-24. doi: 10.1016/j.bbrc.2018.08.064. Epub 2018 Aug 17. Biochem Biophys Res Commun. 2018. PMID: 30126632