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Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation.
Antib Ther. 2019 Oct;2(4):71-78. doi: 10.1093/abt/tbz009. Epub 2019 Oct 24.
Antib Ther. 2019.
PMID: 31930187
Free PMC article.
Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts.
Pedzisa L, Li X, Rader C, Roush WR.
Pedzisa L, et al.
Org Biomol Chem. 2016 Jun 14;14(22):5141-7. doi: 10.1039/c6ob00775a. Epub 2016 May 17.
Org Biomol Chem. 2016.
PMID: 27184239
Free PMC article.
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Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.
Li X, Patterson JT, Sarkar M, Pedzisa L, Kodadek T, Roush WR, Rader C.
Li X, et al. Among authors: pedzisa l.
Bioconjug Chem. 2015 Nov 18;26(11):2243-8. doi: 10.1021/acs.bioconjchem.5b00244. Epub 2015 Jul 24.
Bioconjug Chem. 2015.
PMID: 26161903
Free PMC article.
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Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.
Nanna AR, Li X, Walseng E, Pedzisa L, Goydel RS, Hymel D, Burke TR Jr, Roush WR, Rader C.
Nanna AR, et al. Among authors: pedzisa l.
Nat Commun. 2017 Oct 24;8(1):1112. doi: 10.1038/s41467-017-01257-1.
Nat Commun. 2017.
PMID: 29062027
Free PMC article.
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Aliphatic C-H...anion hydrogen bonds: weak contacts or strong interactions?
Pedzisa L, Hay BP.
Pedzisa L, et al.
J Org Chem. 2009 Mar 20;74(6):2554-60. doi: 10.1021/jo900018u.
J Org Chem. 2009.
PMID: 19215106
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