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Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.
Cummings J, Ranson M, Lacasse E, Ganganagari JR, St-Jean M, Jayson G, Durkin J, Dive C. Cummings J, et al. Among authors: dive c. Br J Cancer. 2006 Jul 3;95(1):42-8. doi: 10.1038/sj.bjc.6603220. Br J Cancer. 2006. PMID: 16804528 Free PMC article.
Quantitative multiplexed quantum dot immunohistochemistry.
Sweeney E, Ward TH, Gray N, Womack C, Jayson G, Hughes A, Dive C, Byers R. Sweeney E, et al. Among authors: dive c. Biochem Biophys Res Commun. 2008 Sep 19;374(2):181-6. doi: 10.1016/j.bbrc.2008.06.127. Epub 2008 Jul 11. Biochem Biophys Res Commun. 2008. PMID: 18621021
Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer.
Dean E, Jodrell D, Connolly K, Danson S, Jolivet J, Durkin J, Morris S, Jowle D, Ward T, Cummings J, Dickinson G, Aarons L, Lacasse E, Robson L, Dive C, Ranson M. Dean E, et al. Among authors: dive c. J Clin Oncol. 2009 Apr 1;27(10):1660-6. doi: 10.1200/JCO.2008.19.5677. Epub 2009 Feb 23. J Clin Oncol. 2009. PMID: 19237630 Clinical Trial.
Identification of early predictive imaging biomarkers and their relationship to serological angiogenic markers in patients with ovarian cancer with residual disease following cytotoxic therapy.
Mitchell CL, O'Connor JPB, Jackson A, Parker GJM, Roberts C, Watson Y, Cheung S, Davies K, Buonaccorsi GA, Clamp AR, Hasan J, Byrd L, Backen A, Dive C, Jayson GC. Mitchell CL, et al. Among authors: dive c. Ann Oncol. 2010 Oct;21(10):1982-1989. doi: 10.1093/annonc/mdq079. Epub 2010 Mar 29. Ann Oncol. 2010. PMID: 20351070 Free article.
429 results