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Page 1
A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.
Steinbach RJ, Haese NN, Smith JL, Colgin LMA, MacAllister RP, Greene JM, Parkins CJ, Kempton JB, Porsov E, Wang X, Renner LM, McGill TJ, Dozier BL, Kreklywich CN, Andoh TF, Grafe MR, Pecoraro HL, Hodge T, Friedman RM, Houser LA, Morgan TK, Stenzel P, Lindner JR, Schelonka RL, Sacha JB, Roberts VHJ, Neuringer M, Brigande JV, Kroenke CD, Frias AE, Lewis AD, Kelleher MA, Hirsch AJ, Streblow DN. Steinbach RJ, et al. Among authors: sacha jb. PLoS One. 2020 Jan 14;15(1):e0227676. doi: 10.1371/journal.pone.0227676. eCollection 2020. PLoS One. 2020. PMID: 31935257 Free PMC article.
Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques.
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, Colgin LM, Axthelm M, Messaoudi I, Sacha JB, Burton DR, Forthal DN, Hessell AJ, Haigwood NL. Jaworski JP, et al. Among authors: sacha jb. J Virol. 2013 Oct;87(19):10447-59. doi: 10.1128/JVI.00049-13. Epub 2013 Jul 24. J Virol. 2013. PMID: 23885083 Free PMC article.
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques.
Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, Reed J, Sutton WF, Hammond KB, Cheever TA, Barnette PT, Legasse AW, Planer S, Stanton JJ, Pegu A, Chen X, Wang K, Siess D, Burke D, Park BS, Axthelm MK, Lewis A, Hirsch VM, Graham BS, Mascola JR, Sacha JB, Haigwood NL. Hessell AJ, et al. Among authors: sacha jb. Nat Med. 2016 Apr;22(4):362-8. doi: 10.1038/nm.4063. Epub 2016 Mar 21. Nat Med. 2016. PMID: 26998834 Free PMC article.
MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.
Greene JM, Dash P, Roy S, McMurtrey C, Awad W, Reed JS, Hammond KB, Abdulhaqq S, Wu HL, Burwitz BJ, Roth BF, Morrow DW, Ford JC, Xu G, Bae JY, Crank H, Legasse AW, Dang TH, Greenaway HY, Kurniawan M, Gold MC, Harriff MJ, Lewinsohn DA, Park BS, Axthelm MK, Stanton JJ, Hansen SG, Picker LJ, Venturi V, Hildebrand W, Thomas PG, Lewinsohn DM, Adams EJ, Sacha JB. Greene JM, et al. Among authors: sacha jb. Mucosal Immunol. 2017 May;10(3):802-813. doi: 10.1038/mi.2016.91. Epub 2016 Oct 19. Mucosal Immunol. 2017. PMID: 27759023 Free PMC article.
Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques.
Burwitz BJ, Malouli D, Bimber BN, Reed JS, Ventura AB, Hancock MH, Uebelhoer LS, Bhusari A, Hammond KB, Espinosa Trethewy RG, Klug A, Legasse AW, Axthelm MK, Nelson JA, Park BS, Streblow DN, Hansen SG, Picker LJ, Früh K, Sacha JB. Burwitz BJ, et al. Among authors: sacha jb. PLoS Pathog. 2016 Nov 9;12(11):e1006014. doi: 10.1371/journal.ppat.1006014. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27829026 Free PMC article.
Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication.
Ericsen AJ, Lauck M, Mohns MS, DiNapoli SR, Mutschler JP, Greene JM, Weinfurter JT, Lehrer-Brey G, Prall TM, Gieger SM, Buechler CR, Crosno KA, Peterson EJ, Reynolds MR, Wiseman RW, Burwitz BJ, Estes JD, Sacha JB, Friedrich TC, Brenchley JM, O'Connor DH. Ericsen AJ, et al. Among authors: sacha jb. PLoS Pathog. 2016 Dec 7;12(12):e1006048. doi: 10.1371/journal.ppat.1006048. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27926931 Free PMC article.
Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes.
Burwitz BJ, Wu HL, Abdulhaqq S, Shriver-Munsch C, Swanson T, Legasse AW, Hammond KB, Junell SL, Reed JS, Bimber BN, Greene JM, Webb GM, Northrup M, Laub W, Kievit P, MacAllister R, Axthelm MK, Ducore R, Lewis A, Colgin LMA, Hobbs T, Martin LD, Ferguson B, Thomas CR Jr, Panoskaltsis-Mortari A, Meyers G, Stanton JJ, Maziarz RT, Sacha JB. Burwitz BJ, et al. Among authors: sacha jb. Nat Commun. 2017 Nov 10;8(1):1418. doi: 10.1038/s41467-017-01631-z. Nat Commun. 2017. PMID: 29127275 Free PMC article.
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques.
Wu HL, Wiseman RW, Hughes CM, Webb GM, Abdulhaqq SA, Bimber BN, Hammond KB, Reed JS, Gao L, Burwitz BJ, Greene JM, Ferrer F, Legasse AW, Axthelm MK, Park BS, Brackenridge S, Maness NJ, McMichael AJ, Picker LJ, O'Connor DH, Hansen SG, Sacha JB. Wu HL, et al. Among authors: sacha jb. J Immunol. 2018 Jan 1;200(1):49-60. doi: 10.4049/jimmunol.1700841. Epub 2017 Nov 17. J Immunol. 2018. PMID: 29150562 Free PMC article.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: sacha jb. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.
Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity.
Shapiro MB, Cheever T, Malherbe DC, Pandey S, Reed J, Yang ES, Wang K, Pegu A, Chen X, Siess D, Burke D, Henderson H, Lewinsohn R, Fischer M, Stanton JJ, Axthelm MK, Kahl C, Park B, Lewis AD, Sacha JB, Mascola JR, Hessell AJ, Haigwood NL. Shapiro MB, et al. Among authors: sacha jb. Nat Commun. 2020 Jan 7;11(1):70. doi: 10.1038/s41467-019-13972-y. Nat Commun. 2020. PMID: 31911610 Free PMC article.
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