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Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JK, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Toepfer CN, et al. Among authors: cloonan p. Circulation. 2020 Mar 10;141(10):828-842. doi: 10.1161/CIRCULATIONAHA.119.042339. Epub 2020 Jan 27. Circulation. 2020. PMID: 31983222 Free PMC article.
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients.
Pua CJ, Tham N, Chin CWL, Walsh R, Khor CC, Toepfer CN, Repetti GG, Garfinkel AC, Ewoldt JF, Cloonan P, Chen CS, Lim SQ, Cai J, Loo LY, Kong SC, Chiang CWK, Whiffin N, de Marvao A, Lio PM, Hii AA, Yang CX, Le TT, Bylstra Y, Lim WK, Teo JX, Padilha K, Silva GV, Pan B, Govind R, Buchan RJ, Barton PJR, Tan P, Foo R, Yip JWL, Wong RCC, Chan WX, Pereira AC, Tang HC, Jamuar SS, Ware JS, Seidman JG, Seidman CE, Cook SA. Pua CJ, et al. Among authors: cloonan p. Circ Genom Precis Med. 2020 Oct;13(5):424-434. doi: 10.1161/CIRCGEN.119.002823. Epub 2020 Aug 20. Circ Genom Precis Med. 2020. PMID: 32815737 Free PMC article.
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.
Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS. Zhang K, et al. Among authors: cloonan pe. Sci Adv. 2021 Oct 15;7(42):eabh3995. doi: 10.1126/sciadv.abh3995. Epub 2021 Oct 15. Sci Adv. 2021. PMID: 34652945 Free PMC article.
Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue.
Javor J, Ewoldt JK, Cloonan PE, Chopra A, Luu RJ, Freychet G, Zhernenkov M, Ludwig K, Seidman JG, Seidman CE, Chen CS, Bishop DJ. Javor J, et al. Among authors: cloonan pe. Microsyst Nanoeng. 2021 Jan 27;7:10. doi: 10.1038/s41378-020-00234-x. eCollection 2021. Microsyst Nanoeng. 2021. PMID: 34567727 Free PMC article.
Frontline hospital workers and the worker safety/patient safety nexus.
Sokas R, Braun B, Chenven L, Cloonan P, Fagan K, Hemphill RR, Hogan E, Storey E. Sokas R, et al. Among authors: cloonan p. Jt Comm J Qual Patient Saf. 2013 Apr;39(4):185-92. doi: 10.1016/s1553-7250(13)39025-4. Jt Comm J Qual Patient Saf. 2013. PMID: 23641538 Free PMC article. No abstract available.
28 results