Abu-Remaileh M - Search Results

1

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.

Weber RA, Yen FS, Nicholson SPV, Alwaseem H, Bayraktar EC, Alam M, Timson RC, La K, Abu-Remaileh M, Molina H, Birsoy K. Weber RA, et al. Mol Cell. 2020 Feb 6;77(3):645-655.e7. doi: 10.1016/j.molcel.2020.01.003. Epub 2020 Jan 23. Mol Cell. 2020. PMID: 31983508 Free PMC article.

2

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.

Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM. Birsoy K, et al. Cell. 2015 Jul 30;162(3):540-51. doi: 10.1016/j.cell.2015.07.016. Cell. 2015. PMID: 26232224 Free PMC article.

3

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.

Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, Liu CM, Zhou M, Koh MJ, Chung H, Davidson SM, Luengo A, Wang AQ, Xu X, Yasgar A, Liu L, Rai G, Westover KD, Vander Heiden MG, Shen M, Gray NS, Boxer MB, Sabatini DM. Pacold ME, et al. Nat Chem Biol. 2016 Jun;12(6):452-8. doi: 10.1038/nchembio.2070. Epub 2016 Apr 25. Nat Chem Biol. 2016. PMID: 27110680 Free PMC article.

4

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo.

Bayraktar EC, Baudrier L, Özerdem C, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Cangelosi AL, Sabatini DM, Birsoy K, Chen WW. Bayraktar EC, et al. Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):303-312. doi: 10.1073/pnas.1816656115. Epub 2018 Dec 12. Proc Natl Acad Sci U S A. 2019. PMID: 30541894 Free PMC article.

5

An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.

Scharenberg SG, Dong W, Ghoochani A, Nyame K, Levin-Konigsberg R, Krishnan AR, Rawat ES, Spees K, Bassik MC, Abu-Remaileh M. Scharenberg SG, et al. Sci Adv. 2023 Apr 21;9(16):eadf8966. doi: 10.1126/sciadv.adf8966. Epub 2023 Apr 19. Sci Adv. 2023. PMID: 37075117 Free PMC article.

6

The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase.

Medoh UN, Hims A, Chen JY, Ghoochani A, Nyame K, Dong W, Abu-Remaileh M. Medoh UN, et al. Among authors: abu remaileh m. Science. 2023 Sep 15;381(6663):1182-1189. doi: 10.1126/science.adg9288. Epub 2023 Sep 14. Science. 2023. PMID: 37708259

7

Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals.

Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi CR. Pedram K, et al. Proc Natl Acad Sci U S A. 2022 Sep 27;119(39):e2117105119. doi: 10.1073/pnas.2117105119. Epub 2022 Sep 19. Proc Natl Acad Sci U S A. 2022. PMID: 36122205 Free PMC article.

8

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.

Wyant GA, Abu-Remaileh M, Wolfson RL, Chen WW, Freinkman E, Danai LV, Vander Heiden MG, Sabatini DM. Wyant GA, et al. Cell. 2017 Oct 19;171(3):642-654.e12. doi: 10.1016/j.cell.2017.09.046. Cell. 2017. PMID: 29053970 Free PMC article.

9

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.

Laqtom NN, Dong W, Medoh UN, Cangelosi AL, Dharamdasani V, Chan SH, Kunchok T, Lewis CA, Heinze I, Tang R, Grimm C, Dang Do AN, Porter FD, Ori A, Sabatini DM, Abu-Remaileh M. Laqtom NN, et al. Nature. 2022 Sep;609(7929):1005-1011. doi: 10.1038/s41586-022-05221-y. Epub 2022 Sep 21. Nature. 2022. PMID: 36131016 Free PMC article.

10

WWOX somatic ablation in skeletal muscles alters glucose metabolism.

Abu-Remaileh M, Abu-Remaileh M, Akkawi R, Knani I, Udi S, Pacold ME, Tam J, Aqeilan RI. Abu-Remaileh M, et al. Mol Metab. 2019 Apr;22:132-140. doi: 10.1016/j.molmet.2019.01.010. Epub 2019 Jan 31. Mol Metab. 2019. PMID: 30755385 Free PMC article.

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