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Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.
Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK. Xu W, et al. Among authors: brett tj. Cell Host Microbe. 2014 Aug 13;16(2):187-200. doi: 10.1016/j.chom.2014.07.008. Cell Host Microbe. 2014. PMID: 25121748 Free PMC article.
Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ. Yurtsever Z, et al. Among authors: brett tj. J Biol Chem. 2012 Dec 7;287(50):42138-49. doi: 10.1074/jbc.M112.410282. Epub 2012 Oct 30. J Biol Chem. 2012. PMID: 23112050 Free PMC article.
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
Alevy YG, Patel AC, Romero AG, Patel DA, Tucker J, Roswit WT, Miller CA, Heier RF, Byers DE, Brett TJ, Holtzman MJ. Alevy YG, et al. Among authors: brett tj. J Clin Invest. 2012 Dec;122(12):4555-68. doi: 10.1172/JCI64896. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187130 Free PMC article.
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