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865 results

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Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.
Huang SH, Ren Y, Thomas AS, Chan D, Mueller S, Ward AR, Patel S, Bollard CM, Cruz CR, Karandish S, Truong R, Macedo AB, Bosque A, Kovacs C, Benko E, Piechocka-Trocha A, Wong H, Jeng E, Nixon DF, Ho YC, Siliciano RF, Walker BD, Jones RB. Huang SH, et al. Among authors: jones rb. J Clin Invest. 2018 Feb 1;128(2):876-889. doi: 10.1172/JCI97555. Epub 2018 Jan 22. J Clin Invest. 2018. PMID: 29355843 Free PMC article.
Dual TLR2 and TLR7 agonists as HIV latency-reversing agents.
Macedo AB, Novis CL, De Assis CM, Sorensen ES, Moszczynski P, Huang SH, Ren Y, Spivak AM, Jones RB, Planelles V, Bosque A. Macedo AB, et al. Among authors: jones rb. JCI Insight. 2018 Oct 4;3(19):e122673. doi: 10.1172/jci.insight.122673. JCI Insight. 2018. PMID: 30282829 Free PMC article.
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion.
Pinzone MR, VanBelzen DJ, Weissman S, Bertuccio MP, Cannon L, Venanzi-Rullo E, Migueles S, Jones RB, Mota T, Joseph SB, Groen K, Pasternak AO, Hwang WT, Sherman B, Vourekas A, Nunnari G, O'Doherty U. Pinzone MR, et al. Among authors: jones rb. Nat Commun. 2019 Feb 13;10(1):728. doi: 10.1038/s41467-019-08431-7. Nat Commun. 2019. PMID: 30760706 Free PMC article.
Brief Report: HIV Antibodies Decline During Antiretroviral Therapy but Remain Correlated With HIV DNA and HIV-Specific T-Cell Responses.
Keating SM, Jones RB, Lalama CM, Bosch RJ, McMahon D, Hampton D, Cyktor J, Eron JJ, Mellors JW, Busch MP, Gandhi RT; ACTG 5321 Team. Keating SM, et al. Among authors: jones rb. J Acquir Immune Defic Syndr. 2019 Aug 15;81(5):594-599. doi: 10.1097/QAI.0000000000002080. J Acquir Immune Defic Syndr. 2019. PMID: 31045647 Free PMC article.
Have Cells Harboring the HIV Reservoir Been Immunoedited?
Huang SH, McCann CD, Mota TM, Wang C, Lipkin SM, Jones RB. Huang SH, et al. Among authors: jones rb. Front Immunol. 2019 Aug 6;10:1842. doi: 10.3389/fimmu.2019.01842. eCollection 2019. Front Immunol. 2019. PMID: 31447850 Free PMC article.
BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo.
Ren Y, Huang SH, Patel S, Alberto WDC, Magat D, Ahimovic D, Macedo AB, Durga R, Chan D, Zale E, Mota TM, Truong R, Rohwetter T, McCann CD, Kovacs CM, Benko E, Wimpelberg A, Cannon C, Hardy WD, Bosque A, Bollard CM, Jones RB. Ren Y, et al. Among authors: jones rb. J Clin Invest. 2020 May 1;130(5):2542-2559. doi: 10.1172/JCI132374. J Clin Invest. 2020. PMID: 32027622 Free PMC article.
Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal.
Mota TM, McCann CD, Danesh A, Huang SH, Magat DB, Ren Y, Leyre L, Bui TD, Rohwetter TM, Kovacs CM, Benko E, MacLaren L, Wimpelberg A, Cannon CM, Hardy WD, Safrit JT, Jones RB. Mota TM, et al. Among authors: jones rb. J Virol. 2020 Apr 16;94(9):e01845-19. doi: 10.1128/JVI.01845-19. Print 2020 Apr 16. J Virol. 2020. PMID: 32051267 Free PMC article.
865 results