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A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet.
Sari G, Meester EJ, van der Zee LC, Wouters K, van Lennep JR, Peppelenbosch M, Boonstra A, Van der Heiden K, Mulder MMT, Vanwolleghem T. Sari G, et al. Among authors: wouters k. Biochem Biophys Res Commun. 2020 Apr 2;524(2):510-515. doi: 10.1016/j.bbrc.2020.01.067. Epub 2020 Feb 1. Biochem Biophys Res Commun. 2020. PMID: 32014257 Free article.
Adipose tissue macrophages do not affect atherosclerosis development in mice.
Bijnen M, van de Gaar J, Vroomen M, Gijbels MJ, de Winther M, Schalkwijk CG, Wouters K. Bijnen M, et al. Among authors: wouters k. Atherosclerosis. 2019 Feb;281:31-37. doi: 10.1016/j.atherosclerosis.2018.12.010. Epub 2018 Dec 19. Atherosclerosis. 2019. PMID: 30654169 Free article.
Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice.
Vanschoonbeek K, Wouters K, van der Meijden PE, van Gorp PJ, Feijge MA, Herfs M, Schurgers LJ, Hofker MH, de Maat MP, Heemskerk JW. Vanschoonbeek K, et al. Among authors: wouters k. Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2023-9. doi: 10.1161/ATVBAHA.107.156992. Epub 2008 Aug 28. Arterioscler Thromb Vasc Biol. 2008. PMID: 18757293
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype.
Hanssen NM, Wouters K, Huijberts MS, Gijbels MJ, Sluimer JC, Scheijen JL, Heeneman S, Biessen EA, Daemen MJ, Brownlee M, de Kleijn DP, Stehouwer CD, Pasterkamp G, Schalkwijk CG. Hanssen NM, et al. Among authors: wouters k. Eur Heart J. 2014 May;35(17):1137-46. doi: 10.1093/eurheartj/eht402. Epub 2013 Oct 14. Eur Heart J. 2014. PMID: 24126878
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: wouters k. PLoS One. 2012;7(1):e30668. doi: 10.1371/journal.pone.0030668. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295101 Free PMC article.
303 results