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Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia.
Malcikova J, Stano-Kozubik K, Tichy B, Kantorova B, Pavlova S, Tom N, Radova L, Smardova J, Pardy F, Doubek M, Brychtova Y, Mraz M, Plevova K, Diviskova E, Oltova A, Mayer J, Pospisilova S, Trbusek M. Malcikova J, et al. Among authors: tom n. Leukemia. 2015 Apr;29(4):877-85. doi: 10.1038/leu.2014.297. Epub 2014 Oct 28. Leukemia. 2015. PMID: 25287991 Free PMC article.
Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients.
Kantorova B, Malcikova J, Brazdilova K, Borsky M, Plevova K, Smardova J, Radova L, Tom N, Trbusek M, Diviskova E, Francova HS, Navrkalova V, Doubek M, Brychtova Y, Mayer J, Pospisilova S. Kantorova B, et al. Among authors: tom n. Br J Haematol. 2017 Sep;178(6):979-982. doi: 10.1111/bjh.14176. Epub 2016 Jul 29. Br J Haematol. 2017. PMID: 27470445 Free article. No abstract available.
Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status.
Kubesova B, Pavlova S, Malcikova J, Kabathova J, Radova L, Tom N, Tichy B, Plevova K, Kantorova B, Fiedorova K, Slavikova M, Bystry V, Kissova J, Gisslinger B, Gisslinger H, Penka M, Mayer J, Kralovics R, Pospisilova S, Doubek M. Kubesova B, et al. Among authors: tom n. Leukemia. 2018 Feb;32(2):450-461. doi: 10.1038/leu.2017.230. Epub 2017 Jul 24. Leukemia. 2018. PMID: 28744014 Free PMC article.
The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice.
Culen M, Kosarova Z, Jeziskova I, Folta A, Chovancova J, Loja T, Tom N, Bystry V, Janeckova V, Dvorakova D, Mayer J, Racil Z. Culen M, et al. Among authors: tom n. J Cancer Res Clin Oncol. 2018 Jul;144(7):1239-1251. doi: 10.1007/s00432-018-2652-2. Epub 2018 May 2. J Cancer Res Clin Oncol. 2018. PMID: 29721667
Prognostic significance of mutation profile at diagnosis and mutation persistence during disease remission in adult acute myeloid leukaemia patients.
Folta A, Culen M, Jeziskova I, Herudkova Z, Tom N, Hlubinkova T, Janeckova V, Durinikova A, Vydra J, Semerad L, Dvorakova D, Remesova H, Cerovska E, Cetkovsky P, Jindra P, Szotkowski T, Zak P, Mayer J, Racil Z. Folta A, et al. Among authors: tom n. Br J Haematol. 2019 Jul;186(2):300-310. doi: 10.1111/bjh.15916. Epub 2019 Apr 9. Br J Haematol. 2019. PMID: 30968396 Free article. Clinical Trial.
Impact of gene mutations and chromosomal aberrations on progression-free survival in chronic lymphocytic leukemia patients treated with front-line chemoimmunotherapy: Clinical practice experience.
Spunarova M, Tom N, Pavlova S, Mraz M, Brychtova Y, Doubek M, Panovska A, Skuhrova Francova H, Brzobohata A, Pospisilova S, Mayer J, Trbusek M. Spunarova M, et al. Among authors: tom n. Leuk Res. 2019 Jun;81:75-81. doi: 10.1016/j.leukres.2019.04.015. Epub 2019 Apr 25. Leuk Res. 2019. PMID: 31054420
43 results