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Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy.
Tan-Garcia A, Lai F, Sheng Yeong JP, Irac SE, Ng PY, Msallam R, Tatt Lim JC, Wai LE, Tham CYL, Choo SP, Lim T, Young DY, D'Ambrosio R, Degasperi E, Perbellini R, Newell E, Le Bert N, Ginhoux F, Bertoletti A, Chen Q, Dutertre CA. Tan-Garcia A, et al. Among authors: chen q. JHEP Rep. 2019 Dec 6;2(1):100062. doi: 10.1016/j.jhepr.2019.11.006. eCollection 2020 Feb. JHEP Rep. 2019. PMID: 32039403 Free PMC article.
Mapping the human DC lineage through the integration of high-dimensional techniques.
See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F. See P, et al. Among authors: chen j, chen q. Science. 2017 Jun 9;356(6342):eaag3009. doi: 10.1126/science.aag3009. Epub 2017 May 4. Science. 2017. PMID: 28473638 Free PMC article.
Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease.
Tan-Garcia A, Wai LE, Zheng D, Ceccarello E, Jo J, Banu N, Khakpoor A, Chia A, Tham CYL, Tan AT, Hong M, Keng CT, Rivino L, Tan KC, Lee KH, Lim SG, Newell EW, Pavelka N, Chen J, Ginhoux F, Chen Q, Bertoletti A, Dutertre CA. Tan-Garcia A, et al. Among authors: chen j, chen q. J Hepatol. 2017 Sep;67(3):490-500. doi: 10.1016/j.jhep.2017.04.023. Epub 2017 May 5. J Hepatol. 2017. PMID: 28483682
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice.
Her Z, Tan JHL, Lim YS, Tan SY, Chan XY, Tan WWS, Liu M, Yong KSM, Lai F, Ceccarello E, Zheng Z, Fan Y, Chang KTE, Sun L, Chang SC, Chin CL, Lee GH, Dan YY, Chan YS, Lim SG, Chan JKY, Chandy KG, Chen Q. Her Z, et al. Among authors: chen q. Front Immunol. 2020 Sep 11;11:580968. doi: 10.3389/fimmu.2020.580968. eCollection 2020. Front Immunol. 2020. PMID: 33013934 Free PMC article.
Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics.
Yong KSM, Her Z, Tan SY, Tan WWS, Liu M, Lai F, Heng SM, Fan Y, Chang KTE, Wang CI, Chan JKY, Chen J, Chen Q. Yong KSM, et al. Among authors: chen j, chen q. Front Immunol. 2020 Oct 15;11:553362. doi: 10.3389/fimmu.2020.553362. eCollection 2020. Front Immunol. 2020. PMID: 33193321 Free PMC article.
Establishment of Humanized Mice for the Study of HBV.
Lai F, Wee CYY, Chen Q. Lai F, et al. Among authors: chen q. Front Immunol. 2021 Feb 19;12:638447. doi: 10.3389/fimmu.2021.638447. eCollection 2021. Front Immunol. 2021. PMID: 33679796 Free PMC article. Review.
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma.
Lam MSY, Reales-Calderon JA, Ow JR, Aw JJY, Tan D, Vijayakumar R, Ceccarello E, Tabaglio T, Lim YT, Chien WL, Lai F, Tanoto AT, Chen Q, Sobota RM, Adriani G, Bertoletti A, Guccione E, Pavesi A. Lam MSY, et al. Among authors: chen q. Nat Commun. 2023 Feb 2;14(1):563. doi: 10.1038/s41467-023-36160-5. Nat Commun. 2023. PMID: 36732506 Free PMC article.
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