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Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC. Wunderlich FT, et al. Among authors: pasparakis m. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1297-302. doi: 10.1073/pnas.0707849104. Epub 2008 Jan 23. Proc Natl Acad Sci U S A. 2008. PMID: 18216263 Free PMC article.
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P, Basic M, Bleich A, Kelliher M, Pasparakis M. Dannappel M, et al. Among authors: pasparakis m. Nature. 2014 Sep 4;513(7516):90-4. doi: 10.1038/nature13608. Epub 2014 Aug 17. Nature. 2014. PMID: 25132550 Free PMC article.
Synchronized renal tubular cell death involves ferroptosis.
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S. Linkermann A, et al. Among authors: pasparakis m. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385600 Free PMC article.
Necroptosis and its role in inflammation.
Pasparakis M, Vandenabeele P. Pasparakis M, et al. Nature. 2015 Jan 15;517(7534):311-20. doi: 10.1038/nature14191. Nature. 2015. PMID: 25592536 Review.
NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P, Kelliher M, Pasparakis M. Kondylis V, et al. Among authors: pasparakis m. Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001. Cancer Cell. 2015. PMID: 26555174 Free PMC article.
196 results