Wang H - Search Results

1

Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke.

Naito MG, Xu D, Amin P, Lee J, Wang H, Li W, Kelliher M, Pasparakis M, Yuan J. Naito MG, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4959-4970. doi: 10.1073/pnas.1916427117. Epub 2020 Feb 18. Proc Natl Acad Sci U S A. 2020. PMID: 32071228 Free PMC article.

2

FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation.

Xiao J, Zhang T, Xu D, Wang H, Cai Y, Jin T, Liu M, Jin M, Wu K, Yuan J. Xiao J, et al. Among authors: wang h. Genes Dev. 2015 Jan 15;29(2):184-96. doi: 10.1101/gad.252528.114. Genes Dev. 2015. PMID: 25593308 Free PMC article.

3

PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP.

Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar AK, Wei H, Li Y, Sun SC, Yuan J. Wang H, et al. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11944-11949. doi: 10.1073/pnas.1715742114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078411 Free PMC article.

4

Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.

Meng H, Liu Z, Li X, Wang H, Jin T, Wu G, Shan B, Christofferson DE, Qi C, Yu Q, Li Y, Yuan J. Meng H, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2001-E2009. doi: 10.1073/pnas.1722013115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440439 Free PMC article.

5

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.

Amin P, Florez M, Najafov A, Pan H, Geng J, Ofengeim D, Dziedzic SA, Wang H, Barrett VJ, Ito Y, LaVoie MJ, Yuan J. Amin P, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5944-E5953. doi: 10.1073/pnas.1806973115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891719 Free PMC article.

6

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.

Xu D, Zhao H, Jin M, Zhu H, Shan B, Geng J, Dziedzic SA, Amin P, Mifflin L, Naito MG, Najafov A, Xing J, Yan L, Liu J, Qin Y, Hu X, Wang H, Zhang M, Manuel VJ, Tan L, He Z, Sun ZJ, Lee VMY, Wagner G, Yuan J. Xu D, et al. Among authors: wang h. Nature. 2020 Nov;587(7832):133-138. doi: 10.1038/s41586-020-2757-z. Epub 2020 Sep 23. Nature. 2020. PMID: 32968279

7

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.

Najafov A, Luu HS, Mookhtiar AK, Mifflin L, Xia HG, Amin PP, Ordureau A, Wang H, Yuan J. Najafov A, et al. Among authors: wang h. Mol Cell. 2021 Jan 21;81(2):370-385.e7. doi: 10.1016/j.molcel.2020.11.008. Epub 2020 Dec 2. Mol Cell. 2021. PMID: 33271062 Free article.

8

Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease.

Zou C, Mifflin L, Hu Z, Zhang T, Shan B, Wang H, Xing X, Zhu H, Adiconis X, Levin JZ, Li F, Liu CF, Liu JS, Yuan J. Zou C, et al. Among authors: wang h. Cell Rep. 2020 Dec 8;33(10):108447. doi: 10.1016/j.celrep.2020.108447. Cell Rep. 2020. PMID: 33296651 Free article.

9

NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.

Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito MG, Mifflin L, Liu Z, Najafov A, Pan H, Shan B, Li Y, Zhu ZJ, Yuan J. Wang H, et al. Nat Commun. 2021 Aug 10;12(1):4826. doi: 10.1038/s41467-021-25157-7. Nat Commun. 2021. PMID: 34376696 Free PMC article.

10

Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response.

Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. Li W, et al. Among authors: wang h. Cell Res. 2022 Jul;32(7):621-637. doi: 10.1038/s41422-022-00673-3. Epub 2022 Jun 3. Cell Res. 2022. PMID: 35661830 Free PMC article.

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