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Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers.
Coussy F, El Botty R, Lavigne M, Gu C, Fuhrmann L, Briaux A, de Koning L, Dahmani A, Montaudon E, Morisset L, Huguet L, Sourd L, Painsec P, Chateau-Joubert S, Larcher T, Vacher S, Melaabi S, Salomon AV, Marangoni E, Bieche I. Coussy F, et al. Among authors: fuhrmann l. J Hematol Oncol. 2020 Feb 22;13(1):13. doi: 10.1186/s13045-020-0846-y. J Hematol Oncol. 2020. PMID: 32087759 Free PMC article.
Control of MT1-MMP transport by atypical PKC during breast-cancer progression.
Rossé C, Lodillinsky C, Fuhrmann L, Nourieh M, Monteiro P, Irondelle M, Lagoutte E, Vacher S, Waharte F, Paul-Gilloteaux P, Romao M, Sengmanivong L, Linch M, van Lint J, Raposo G, Vincent-Salomon A, Bièche I, Parker PJ, Chavrier P. Rossé C, et al. Among authors: fuhrmann l. Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1872-9. doi: 10.1073/pnas.1400749111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753582 Free PMC article.
p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer.
Lodillinsky C, Infante E, Guichard A, Chaligné R, Fuhrmann L, Cyrta J, Irondelle M, Lagoutte E, Vacher S, Bonsang-Kitzis H, Glukhova M, Reyal F, Bièche I, Vincent-Salomon A, Chavrier P. Lodillinsky C, et al. Among authors: fuhrmann l. Oncogene. 2016 Jan 21;35(3):344-57. doi: 10.1038/onc.2015.87. Epub 2015 Apr 20. Oncogene. 2016. PMID: 25893299
Unraveling the Role of Huntingtin in Breast Cancer Metastasis.
Thion MS, McGuire JR, Sousa CM, Fuhrmann L, Fitamant J, Leboucher S, Vacher S, du Montcel ST, Bièche I, Bernet A, Mehlen P, Vincent-Salomon A, Humbert S. Thion MS, et al. Among authors: fuhrmann l. J Natl Cancer Inst. 2015 Aug 20;107(10):djv208. doi: 10.1093/jnci/djv208. Print 2015 Oct. J Natl Cancer Inst. 2015. PMID: 26293574
AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin.
Couderc C, Boin A, Fuhrmann L, Vincent-Salomon A, Mandati V, Kieffer Y, Mechta-Grigoriou F, Del Maestro L, Chavrier P, Vallerand D, Brito I, Dubois T, De Koning L, Bouvard D, Louvard D, Gautreau A, Lallemand D. Couderc C, et al. Among authors: fuhrmann l. Neoplasia. 2016 Jan;18(1):10-24. doi: 10.1016/j.neo.2015.11.010. Neoplasia. 2016. PMID: 26806348 Free PMC article.
Clinical value of R-spondins in triple-negative and metaplastic breast cancers.
Coussy F, Lallemand F, Vacher S, Schnitzler A, Chemlali W, Caly M, Nicolas A, Richon S, Meseure D, El Botty R, De-Plater L, Fuhrmann L, Dubois T, Roman-Roman S, Dangles-Marie V, Marangoni E, Bièche I. Coussy F, et al. Among authors: fuhrmann l. Br J Cancer. 2017 Jun 6;116(12):1595-1603. doi: 10.1038/bjc.2017.131. Epub 2017 May 4. Br J Cancer. 2017. PMID: 28472820 Free PMC article.
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