Law RHP - Search Results

1

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.

Harrington BS, He Y, Khan T, Puttick S, Conroy PJ, Kryza T, Cuda T, Sokolowski KA, Tse BW, Robbins KK, Arachchige BJ, Stehbens SJ, Pollock PM, Reed S, Weroha SJ, Haluska P, Salomon C, Lourie R, Perrin LC, Law RHP, Whisstock JC, Hooper JD. Harrington BS, et al. Among authors: law rhp. Theranostics. 2020 Jan 12;10(5):2095-2114. doi: 10.7150/thno.30736. eCollection 2020. Theranostics. 2020. PMID: 32104500 Free PMC article.

2

Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.

Law RH, Smooker PM, Irving JA, Piedrafita D, Ponting R, Kennedy NJ, Whisstock JC, Pike RN, Spithill TW. Law RH, et al. Infect Immun. 2003 Dec;71(12):6921-32. doi: 10.1128/IAI.71.12.6921-6932.2003. Infect Immun. 2003. PMID: 14638781 Free PMC article.

3

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.

Law RH, Irving JA, Buckle AM, Ruzyla K, Buzza M, Bashtannyk-Puhalovich TA, Beddoe TC, Nguyen K, Worrall DM, Bottomley SP, Bird PI, Rossjohn J, Whisstock JC. Law RH, et al. J Biol Chem. 2005 Jun 10;280(23):22356-64. doi: 10.1074/jbc.M412043200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760906 Free article.

4

An overview of the serpin superfamily.

Law RH, Zhang Q, McGowan S, Buckle AM, Silverman GA, Wong W, Rosado CJ, Langendorf CG, Pike RN, Bird PI, Whisstock JC. Law RH, et al. Genome Biol. 2006;7(5):216. doi: 10.1186/gb-2006-7-5-216. Epub 2006 May 30. Genome Biol. 2006. PMID: 16737556 Free PMC article. Review.

5

The crystal structure of the transthyretin-like protein from Salmonella dublin, a prokaryote 5-hydroxyisourate hydrolase.

Hennebry SC, Law RH, Richardson SJ, Buckle AM, Whisstock JC. Hennebry SC, et al. J Mol Biol. 2006 Jun 23;359(5):1389-99. doi: 10.1016/j.jmb.2006.04.057. Epub 2006 May 11. J Mol Biol. 2006. PMID: 16787778

6

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.

Fenalti G, Law RH, Buckle AM, Langendorf C, Tuck K, Rosado CJ, Faux NG, Mahmood K, Hampe CS, Banga JP, Wilce M, Schmidberger J, Rossjohn J, El-Kabbani O, Pike RN, Smith AI, Mackay IR, Rowley MJ, Whisstock JC. Fenalti G, et al. Nat Struct Mol Biol. 2007 Apr;14(4):280-6. doi: 10.1038/nsmb1228. Epub 2007 Mar 25. Nat Struct Mol Biol. 2007. PMID: 17384644

7

The N terminus of the serpin, tengpin, functions to trap the metastable native state.

Zhang Q, Buckle AM, Law RH, Pearce MC, Cabrita LD, Lloyd GJ, Irving JA, Smith AI, Ruzyla K, Rossjohn J, Bottomley SP, Whisstock JC. Zhang Q, et al. EMBO Rep. 2007 Jul;8(7):658-63. doi: 10.1038/sj.embor.7400986. Epub 2007 Jun 8. EMBO Rep. 2007. PMID: 17557112 Free PMC article.

8

A common fold mediates vertebrate defense and bacterial attack.

Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151

9

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.

Law RH, Sofian T, Kan WT, Horvath AJ, Hitchen CR, Langendorf CG, Buckle AM, Whisstock JC, Coughlin PB. Law RH, et al. Blood. 2008 Feb 15;111(4):2049-52. doi: 10.1182/blood-2007-09-114215. Epub 2007 Dec 6. Blood. 2008. PMID: 18063751 Free article.

10

COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.

Fenalti G, Hampe CS, Arafat Y, Law RH, Banga JP, Mackay IR, Whisstock JC, Buckle AM, Rowley MJ. Fenalti G, et al. Diabetes. 2008 May;57(5):1293-301. doi: 10.2337/db07-1461. Epub 2008 Jan 9. Diabetes. 2008. PMID: 18184926

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