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Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.
Harrington BS, He Y, Khan T, Puttick S, Conroy PJ, Kryza T, Cuda T, Sokolowski KA, Tse BW, Robbins KK, Arachchige BJ, Stehbens SJ, Pollock PM, Reed S, Weroha SJ, Haluska P, Salomon C, Lourie R, Perrin LC, Law RHP, Whisstock JC, Hooper JD. Harrington BS, et al. Among authors: whisstock jc. Theranostics. 2020 Jan 12;10(5):2095-2114. doi: 10.7150/thno.30736. eCollection 2020. Theranostics. 2020. PMID: 32104500 Free PMC article.
An overview of the serpin superfamily.
Law RH, Zhang Q, McGowan S, Buckle AM, Silverman GA, Wong W, Rosado CJ, Langendorf CG, Pike RN, Bird PI, Whisstock JC. Law RH, et al. Among authors: whisstock jc. Genome Biol. 2006;7(5):216. doi: 10.1186/gb-2006-7-5-216. Epub 2006 May 30. Genome Biol. 2006. PMID: 16737556 Free PMC article. Review.
The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Zhang Q, Buckle AM, Law RH, Pearce MC, Cabrita LD, Lloyd GJ, Irving JA, Smith AI, Ruzyla K, Rossjohn J, Bottomley SP, Whisstock JC. Zhang Q, et al. Among authors: whisstock jc. EMBO Rep. 2007 Jul;8(7):658-63. doi: 10.1038/sj.embor.7400986. Epub 2007 Jun 8. EMBO Rep. 2007. PMID: 17557112 Free PMC article.
X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.
Law RH, Sofian T, Kan WT, Horvath AJ, Hitchen CR, Langendorf CG, Buckle AM, Whisstock JC, Coughlin PB. Law RH, et al. Among authors: whisstock jc. Blood. 2008 Feb 15;111(4):2049-52. doi: 10.1182/blood-2007-09-114215. Epub 2007 Dec 6. Blood. 2008. PMID: 18063751 Free article.
A structural basis for loop C-sheet polymerization in serpins.
Zhang Q, Law RH, Bottomley SP, Whisstock JC, Buckle AM. Zhang Q, et al. Among authors: whisstock jc. J Mol Biol. 2008 Mar 7;376(5):1348-59. doi: 10.1016/j.jmb.2007.12.050. Epub 2008 Jan 3. J Mol Biol. 2008. PMID: 18234218
The MACPF/CDC family of pore-forming toxins.
Rosado CJ, Kondos S, Bull TE, Kuiper MJ, Law RH, Buckle AM, Voskoboinik I, Bird PI, Trapani JA, Whisstock JC, Dunstone MA. Rosado CJ, et al. Among authors: whisstock jc. Cell Microbiol. 2008 Sep;10(9):1765-74. doi: 10.1111/j.1462-5822.2008.01191.x. Epub 2008 Jun 28. Cell Microbiol. 2008. PMID: 18564372 Free PMC article. Review.
Structure of granzyme C reveals an unusual mechanism of protease autoinhibition.
Kaiserman D, Buckle AM, Van Damme P, Irving JA, Law RH, Matthews AY, Bashtannyk-Puhalovich T, Langendorf C, Thompson P, Vandekerckhove J, Gevaert K, Whisstock JC, Bird PI. Kaiserman D, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5587-92. doi: 10.1073/pnas.0811968106. Epub 2009 Mar 19. Proc Natl Acad Sci U S A. 2009. PMID: 19299505 Free PMC article.
268 results