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Novel azulene derivatives for the treatment of erectile dysfunction.
Löber S, Hübner H, Buschauer A, Sanna F, Argiolas A, Melis MR, Gmeiner P. Löber S, et al. Among authors: gmeiner p. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7151-4. doi: 10.1016/j.bmcl.2012.09.064. Epub 2012 Oct 6. Bioorg Med Chem Lett. 2012. PMID: 23099096
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.
Keller M, Kuhn KK, Einsiedel J, Hübner H, Biselli S, Mollereau C, Wifling D, Svobodová J, Bernhardt G, Cabrele C, Vanderheyden PM, Gmeiner P, Buschauer A. Keller M, et al. Among authors: gmeiner p. J Med Chem. 2016 Mar 10;59(5):1925-45. doi: 10.1021/acs.jmedchem.5b01495. Epub 2016 Feb 11. J Med Chem. 2016. PMID: 26824643
Structure-Based Design and Discovery of New M2 Receptor Agonists.
Fish I, Stößel A, Eitel K, Valant C, Albold S, Huebner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P. Fish I, et al. Among authors: gmeiner p. J Med Chem. 2017 Nov 22;60(22):9239-9250. doi: 10.1021/acs.jmedchem.7b01113. Epub 2017 Nov 13. J Med Chem. 2017. PMID: 29094937 Free PMC article.
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron A, Peach CJ, Tonello R, Seemann P, Teng S, Latorre R, Huebner H, Weikert D, Rientjes J, Veldhuis NA, Poole DP, Jensen DD, Thomsen ARB, Schmidt BL, Imlach WL, Gmeiner P, Bunnett NW. Hegron A, et al. Among authors: gmeiner p. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2220979120. doi: 10.1073/pnas.2220979120. Epub 2023 May 22. Proc Natl Acad Sci U S A. 2023. PMID: 37216510 Free PMC article.
269 results