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Tuning the Antigen Density Requirement for CAR T-cell Activity.
Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL. Majzner RG, et al. Among authors: myklebust jh. Cancer Discov. 2020 May;10(5):702-723. doi: 10.1158/2159-8290.CD-19-0945. Epub 2020 Mar 19. Cancer Discov. 2020. PMID: 32193224 Free PMC article.
Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma.
Köksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fåne A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S. Köksal H, et al. Among authors: myklebust jh. Blood Adv. 2019 Apr 23;3(8):1230-1243. doi: 10.1182/bloodadvances.2018029678. Blood Adv. 2019. PMID: 30979721 Free PMC article.
Combinatorial CAR design improves target restriction.
Köksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S. Köksal H, et al. Among authors: myklebust jh. J Biol Chem. 2021 Jan-Jun;296:100116. doi: 10.1074/jbc.RA120.016234. Epub 2020 Dec 3. J Biol Chem. 2021. PMID: 33234592 Free PMC article.
What It Takes to Transform a T Cell.
Spasevska I, Myklebust JH. Spasevska I, et al. Among authors: myklebust jh. Cancer Res. 2021 Jun 15;81(12):3160-3161. doi: 10.1158/0008-5472.CAN-21-0784. Cancer Res. 2021. PMID: 34224376
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-cell Lymphoma.
Meriranta L, Sorri S, Huse K, Liu X, Spasevska I, Zafar S, Chowdhury I, Dufva O, Sahlberg E, Tandaric L, Karjalainen-Lindsberg ML, Hyytiainen M, Varjosalo M, Myklebust JH, Leppa S. Meriranta L, et al. Among authors: myklebust jh. Blood Cancer Discov. 2024 Apr 17. doi: 10.1158/2643-3230.BCD-23-0182. Online ahead of print. Blood Cancer Discov. 2024. PMID: 38630892
The targeting of human and mouse B lymphocytes by dasatinib.
Oksvold MP, Duyvestyn JM, Dagger SA, Taylor SJ, Forfang L, Myklebust JH, Smeland EB, Langdon WY. Oksvold MP, et al. Among authors: myklebust jh. Exp Hematol. 2015 May;43(5):352-363.e4. doi: 10.1016/j.exphem.2015.01.008. Epub 2015 Jan 29. Exp Hematol. 2015. PMID: 25641047 Free article.
T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling.
Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjærde OC, Østenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH. Josefsson SE, et al. Among authors: myklebust jh. Clin Cancer Res. 2018 Feb 15;24(4):870-881. doi: 10.1158/1078-0432.CCR-17-2337. Epub 2017 Dec 7. Clin Cancer Res. 2018. PMID: 29217528 Free PMC article.
Human c-SRC kinase (CSK) overexpression makes T cells dummy.
Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fåne A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Wälchli S. Inderberg EM, et al. Among authors: myklebust jh. Cancer Immunol Immunother. 2018 Apr;67(4):525-536. doi: 10.1007/s00262-017-2105-9. Epub 2017 Dec 16. Cancer Immunol Immunother. 2018. PMID: 29248956 Free PMC article.
66 results