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Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Galluzzi L, Vitale I, Warren S, Adjemian S, Agostinis P, Martinez AB, Chan TA, Coukos G, Demaria S, Deutsch E, Draganov D, Edelson RL, Formenti SC, Fucikova J, Gabriele L, Gaipl US, Gameiro SR, Garg AD, Golden E, Han J, Harrington KJ, Hemminki A, Hodge JW, Hossain DMS, Illidge T, Karin M, Kaufman HL, Kepp O, Kroemer G, Lasarte JJ, Loi S, Lotze MT, Manic G, Merghoub T, Melcher AA, Mossman KL, Prosper F, Rekdal Ø, Rescigno M, Riganti C, Sistigu A, Smyth MJ, Spisek R, Stagg J, Strauss BE, Tang D, Tatsuno K, van Gool SW, Vandenabeele P, Yamazaki T, Zamarin D, Zitvogel L, Cesano A, Marincola FM. Galluzzi L, et al. Among authors: rekdal o. J Immunother Cancer. 2020 Mar;8(1):e000337. doi: 10.1136/jitc-2019-000337. J Immunother Cancer. 2020. PMID: 32209603 Free PMC article. Review.
The oncolytic peptide LTX-315 triggers necrotic cell death.
Forveille S, Zhou H, Sauvat A, Bezu L, Müller K, Liu P, Zitvogel L, Pierron G, Rekdal Ø, Kepp O, Kroemer G. Forveille S, et al. Among authors: rekdal o. Cell Cycle. 2015;14(21):3506-12. doi: 10.1080/15384101.2015.1093710. Cell Cycle. 2015. PMID: 26566869 Free PMC article.
The oncolytic peptide LTX-315 triggers immunogenic cell death.
Zhou H, Forveille S, Sauvat A, Yamazaki T, Senovilla L, Ma Y, Liu P, Yang H, Bezu L, Müller K, Zitvogel L, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Among authors: rekdal o. Cell Death Dis. 2016 Mar 10;7(3):e2134. doi: 10.1038/cddis.2016.47. Cell Death Dis. 2016. PMID: 26962684 Free PMC article.
The oncolytic compound LTX-401 targets the Golgi apparatus.
Zhou H, Sauvat A, Gomes-da-Silva LC, Durand S, Forveille S, Iribarren K, Yamazaki T, Souquere S, Bezu L, Müller K, Leduc M, Liu P, Zhao L, Marabelle A, Zitvogel L, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Among authors: rekdal o. Cell Death Differ. 2016 Dec;23(12):2031-2041. doi: 10.1038/cdd.2016.86. Epub 2016 Sep 2. Cell Death Differ. 2016. PMID: 27588704 Free PMC article.
Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.
Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G. Gomes-da-Silva LC, et al. Among authors: rekdal o. EMBO J. 2018 Jul 2;37(13):e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28. EMBO J. 2018. PMID: 29807932 Free PMC article.
Recruitment of LC3 to damaged Golgi apparatus.
Gomes-da-Silva LC, Jimenez AJ, Sauvat A, Xie W, Souquere S, Divoux S, Storch M, Sveinbjørnsson B, Rekdal Ø, Arnaut LG, Kepp O, Kroemer G, Perez F. Gomes-da-Silva LC, et al. Among authors: rekdal o. Cell Death Differ. 2019 Aug;26(8):1467-1484. doi: 10.1038/s41418-018-0221-5. Epub 2018 Oct 22. Cell Death Differ. 2019. PMID: 30349077 Free PMC article.
Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animals.
Zhou H, Mondragón L, Xie W, Mauseth B, Leduc M, Sauvat A, Gomes-da-Silva LC, Forveille S, Iribarren K, Souquere S, Bezu L, Liu P, Zhao L, Zitvogel L, Sveinbjørnsson B, Eksteen JJ, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Among authors: rekdal o. Cell Death Dis. 2018 Oct 23;9(11):1086. doi: 10.1038/s41419-018-1127-3. Cell Death Dis. 2018. PMID: 30352991 Free PMC article.
Tumor lysis with LTX-401 creates anticancer immunity.
Xie W, Mondragón L, Mauseth B, Wang Y, Pol J, Lévesque S, Zhou H, Yamazaki T, Eksteen JJ, Zitvogel L, Sveinbjørnsson B, Rekdal Ø, Kepp O, Kroemer G. Xie W, et al. Among authors: rekdal o. Oncoimmunology. 2019 Apr 13;8(7):1594555. doi: 10.1080/2162402X.2019.1594555. eCollection 2019. Oncoimmunology. 2019. PMID: 31143516 Free PMC article.
73 results